Impaired wound healing in Parkinson’s disease: a hypothesis on altered epidermal growth factor (EGF) and N-methyl-D-aspartate (NMDA) signaling in keratinocytes

Impaired wound healing in Parkinson’s disease: a hypothesis on altered epidermal growth factor (EGF) and N-methyl-D-aspartate (NMDA) signaling in keratinocytes

Abstract Parkinson’s Disease (PD) is a neurodegenerative disorder characterized by the depletion of dopaminergic neurons in the substantia nigra, leading to hallmark motor symptoms such as bradykinesia, tremor, and rigidity. While the focus of PD has been on motor changes, dermatological changes are...

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Bibliographic Details
Main Authors: Caroline Liu, Johanna Ghebrehiwet-Kuflom, Roslyn Rivkah Isseroff, Sara Dahle, Vera Morhenn
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Molecular Medicine
Subjects:
Wound healing
Parkinson’s disease
NMDA
EGF
Psoriasis
Online Access:https://doi.org/10.1186/s10020-025-01247-w
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https://doi.org/10.1186/s10020-025-01247-w

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