Unusual presentation of Stauffer syndrome in post Whipple patient: case report
Stauffer syndrome is a rare paraneoplastic syndrome associated with Renal Cell Cancer (RCC), seen in 3 %–20 % of cases characterized by reversible nonmetastatic anicteric, hepatic dysfunction in the absence of direct hepatobiliary obstruction. We report a case of 78-yr old male, post Whipple surgery...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-07-01
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| Series: | Urology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214442025001366 |
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| author | P.S. Harsha Jinesh Jayadevan C.H. Haris Rajiv Thomas H. Balabhaskar Ramkumar Aiyappan Sharoo Shaneej M |
| author_facet | P.S. Harsha Jinesh Jayadevan C.H. Haris Rajiv Thomas H. Balabhaskar Ramkumar Aiyappan Sharoo Shaneej M |
| author_sort | P.S. Harsha |
| collection | DOAJ |
| description | Stauffer syndrome is a rare paraneoplastic syndrome associated with Renal Cell Cancer (RCC), seen in 3 %–20 % of cases characterized by reversible nonmetastatic anicteric, hepatic dysfunction in the absence of direct hepatobiliary obstruction. We report a case of 78-yr old male, post Whipple surgery who presented with progressive and isolated elevation of Aminotransferases. Imaging confirmed the presence of a renal mass without hepatic metastasis. The patient underwent partial nephrectomy. The patient's clinical course, management, and subsequent resolution of hepatic dysfunction after resection underscore the importance of considering Stauffer syndrome in patients with unexplained liver test abnormalities. |
| format | Article |
| id | doaj-art-6bcb669e682b4b178cef5f7789432935 |
| institution | DOAJ |
| issn | 2214-4420 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Urology Case Reports |
| spelling | doaj-art-6bcb669e682b4b178cef5f77894329352025-08-20T03:09:04ZengElsevierUrology Case Reports2214-44202025-07-016110306510.1016/j.eucr.2025.103065Unusual presentation of Stauffer syndrome in post Whipple patient: case reportP.S. Harsha0Jinesh Jayadevan1C.H. Haris2Rajiv Thomas3H. Balabhaskar4Ramkumar Aiyappan5Sharoo Shaneej M6Corresponding author.; Department of Urology, Government Medical College, Trivandrum, IndiaDepartment of Urology, Government Medical College, Trivandrum, IndiaDepartment of Urology, Government Medical College, Trivandrum, IndiaDepartment of Urology, Government Medical College, Trivandrum, IndiaDepartment of Urology, Government Medical College, Trivandrum, IndiaDepartment of Urology, Government Medical College, Trivandrum, IndiaDepartment of Urology, Government Medical College, Trivandrum, IndiaStauffer syndrome is a rare paraneoplastic syndrome associated with Renal Cell Cancer (RCC), seen in 3 %–20 % of cases characterized by reversible nonmetastatic anicteric, hepatic dysfunction in the absence of direct hepatobiliary obstruction. We report a case of 78-yr old male, post Whipple surgery who presented with progressive and isolated elevation of Aminotransferases. Imaging confirmed the presence of a renal mass without hepatic metastasis. The patient underwent partial nephrectomy. The patient's clinical course, management, and subsequent resolution of hepatic dysfunction after resection underscore the importance of considering Stauffer syndrome in patients with unexplained liver test abnormalities.http://www.sciencedirect.com/science/article/pii/S2214442025001366Stauffers syndromeRenal cancerParaneoplastic syndrome |
| spellingShingle | P.S. Harsha Jinesh Jayadevan C.H. Haris Rajiv Thomas H. Balabhaskar Ramkumar Aiyappan Sharoo Shaneej M Unusual presentation of Stauffer syndrome in post Whipple patient: case report Urology Case Reports Stauffers syndrome Renal cancer Paraneoplastic syndrome |
| title | Unusual presentation of Stauffer syndrome in post Whipple patient: case report |
| title_full | Unusual presentation of Stauffer syndrome in post Whipple patient: case report |
| title_fullStr | Unusual presentation of Stauffer syndrome in post Whipple patient: case report |
| title_full_unstemmed | Unusual presentation of Stauffer syndrome in post Whipple patient: case report |
| title_short | Unusual presentation of Stauffer syndrome in post Whipple patient: case report |
| title_sort | unusual presentation of stauffer syndrome in post whipple patient case report |
| topic | Stauffers syndrome Renal cancer Paraneoplastic syndrome |
| url | http://www.sciencedirect.com/science/article/pii/S2214442025001366 |
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