Portable SERS device for rapid detection of indoxacarb and chlorfenapyr in vegetable juice

Abstract Concerns over health risks associated with mixed pesticide residues have led to a demand for rapid analytical methods. We present a portable surface-enhanced Raman spectroscopy (SERS) device specifically designed for real-time monitoring of indoxacarb (INDX) and chlorfenapyr (CFP) in vegeta...

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Main Authors: Hui Pan, Wei Zhang, Meng Jin, Fang Zhang, Xuelei Chen, Xiao Meng, Hua Shao, Liqun Song, Zhihu Zhang, Cuijuan Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:npj Science of Food
Online Access:https://doi.org/10.1038/s41538-025-00513-9
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author Hui Pan
Wei Zhang
Meng Jin
Fang Zhang
Xuelei Chen
Xiao Meng
Hua Shao
Liqun Song
Zhihu Zhang
Cuijuan Wang
author_facet Hui Pan
Wei Zhang
Meng Jin
Fang Zhang
Xuelei Chen
Xiao Meng
Hua Shao
Liqun Song
Zhihu Zhang
Cuijuan Wang
author_sort Hui Pan
collection DOAJ
description Abstract Concerns over health risks associated with mixed pesticide residues have led to a demand for rapid analytical methods. We present a portable surface-enhanced Raman spectroscopy (SERS) device specifically designed for real-time monitoring of indoxacarb (INDX) and chlorfenapyr (CFP) in vegetable juice. This point-of-use sensor integrates silver nanoparticles with a metal-organic framework (Ag/MOF-808(Zr)) and employs a 19-well quartz plate alongside a portable Raman spectroscopy instrument, facilitating simultaneous adsorption, separation, and detection. Detection limits for INDX and CFP in ginger and spinach juices were 0.26–0.76 ppb. Notably, results closely matched those from liquid chromatography, and in-situ detection was achieved within 2 min without pre-treatment, significantly enhancing efficiency over conventional chromatographic methods. This innovative approach demonstrates substantial potential for detecting pesticide mixtures in non-laboratory settings, presenting a valuable option for point-of-use applications.
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institution Kabale University
issn 2396-8370
language English
publishDate 2025-07-01
publisher Nature Portfolio
record_format Article
series npj Science of Food
spelling doaj-art-6bc745d3d67d4eb5b03674bb894319352025-08-20T04:02:42ZengNature Portfolionpj Science of Food2396-83702025-07-01911810.1038/s41538-025-00513-9Portable SERS device for rapid detection of indoxacarb and chlorfenapyr in vegetable juiceHui Pan0Wei Zhang1Meng Jin2Fang Zhang3Xuelei Chen4Xiao Meng5Hua Shao6Liqun Song7Zhihu Zhang8Cuijuan Wang9Physical and Chemical Laboratory, Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University & Shandong Academy of Medical SciencesPhysical and Chemical Laboratory, Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University & Shandong Academy of Medical SciencesPhysical and Chemical Laboratory, Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University & Shandong Academy of Medical SciencesPhysical and Chemical Laboratory, Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University & Shandong Academy of Medical SciencesPhysical and Chemical Laboratory, Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University & Shandong Academy of Medical SciencesPhysical and Chemical Laboratory, Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University & Shandong Academy of Medical SciencesPhysical and Chemical Laboratory, Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University & Shandong Academy of Medical SciencesPhysical and Chemical Laboratory, Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University & Shandong Academy of Medical SciencesPhysical and Chemical Laboratory, Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University & Shandong Academy of Medical SciencesPhysical and Chemical Laboratory, Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University & Shandong Academy of Medical SciencesAbstract Concerns over health risks associated with mixed pesticide residues have led to a demand for rapid analytical methods. We present a portable surface-enhanced Raman spectroscopy (SERS) device specifically designed for real-time monitoring of indoxacarb (INDX) and chlorfenapyr (CFP) in vegetable juice. This point-of-use sensor integrates silver nanoparticles with a metal-organic framework (Ag/MOF-808(Zr)) and employs a 19-well quartz plate alongside a portable Raman spectroscopy instrument, facilitating simultaneous adsorption, separation, and detection. Detection limits for INDX and CFP in ginger and spinach juices were 0.26–0.76 ppb. Notably, results closely matched those from liquid chromatography, and in-situ detection was achieved within 2 min without pre-treatment, significantly enhancing efficiency over conventional chromatographic methods. This innovative approach demonstrates substantial potential for detecting pesticide mixtures in non-laboratory settings, presenting a valuable option for point-of-use applications.https://doi.org/10.1038/s41538-025-00513-9
spellingShingle Hui Pan
Wei Zhang
Meng Jin
Fang Zhang
Xuelei Chen
Xiao Meng
Hua Shao
Liqun Song
Zhihu Zhang
Cuijuan Wang
Portable SERS device for rapid detection of indoxacarb and chlorfenapyr in vegetable juice
npj Science of Food
title Portable SERS device for rapid detection of indoxacarb and chlorfenapyr in vegetable juice
title_full Portable SERS device for rapid detection of indoxacarb and chlorfenapyr in vegetable juice
title_fullStr Portable SERS device for rapid detection of indoxacarb and chlorfenapyr in vegetable juice
title_full_unstemmed Portable SERS device for rapid detection of indoxacarb and chlorfenapyr in vegetable juice
title_short Portable SERS device for rapid detection of indoxacarb and chlorfenapyr in vegetable juice
title_sort portable sers device for rapid detection of indoxacarb and chlorfenapyr in vegetable juice
url https://doi.org/10.1038/s41538-025-00513-9
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