Selenomethionine alleviates T-2 toxin-induced articular chondrocyte ferroptosis via the system Xc−/GSH/GPX4 axis

Selenomethionine alleviates T-2 toxin-induced articular chondrocyte ferroptosis via the system Xc−/GSH/GPX4 axis

T-2 toxin can induce bone and cartilage development disorder, and oxidative stress plays an important role in it. It is well known that selenomethionine (Se-Met) has antioxidative stress properties and promotes the repair of cartilage lesion, but it remains unclear whether Se-Met can relieve damaged...

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Bibliographic Details
Main Authors: Fang-fang Yu, Juan Zuo, Miao Wang, Shui-yuan Yu, Kang-ting Luo, Tong-tong Sha, Qian Li, Zai-chao Dong, Guo-yu Zhou, Feng Zhang, Xiong Guo, Yue Ba, Yan-jie Wang
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Ecotoxicology and Environmental Safety
Subjects:
T-2 toxin
Se-met
Ferroptosis
Damaged cartilage
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651324016452
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