The human cathelicidin LL-37 has antiviral activity against respiratory syncytial virus.

Respiratory syncytial virus is a leading cause of lower respiratory tract illness among infants, the elderly and immunocompromised individuals. Currently, there is no effective vaccine or disease modifying treatment available and novel interventions are urgently required. Cathelicidins are cationic...

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Bibliographic Details
Main Authors: Silke M Currie, Emily Gwyer Findlay, Brian J McHugh, Annie Mackellar, Tian Man, Derek Macmillan, Hongwei Wang, Paul M Fitch, Jürgen Schwarze, Donald J Davidson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0073659
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