A post-hoc analysis of risk factors for poor quality of life after surgical treatment of spondylodiscitis
Abstract Patient-reported outcome measures for quality of life (QoL) like the Oswestry-Disability-Index (ODI) are useful for a quick, comprehensive and comparable evaluation of spondylodiscitis treatment. While it is known that even after successful surgical treatment, the QoL of spondylodiscitis pa...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-11-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-024-79828-8 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1823862179664756736 |
|---|---|
| author | Krishnan Sircar Dorothee Jochimsen Charlotte Meyer-Schwickerath Norma Jung Nikolaus Kernich Peer Eysel Ayla Yagdiran |
| author_facet | Krishnan Sircar Dorothee Jochimsen Charlotte Meyer-Schwickerath Norma Jung Nikolaus Kernich Peer Eysel Ayla Yagdiran |
| author_sort | Krishnan Sircar |
| collection | DOAJ |
| description | Abstract Patient-reported outcome measures for quality of life (QoL) like the Oswestry-Disability-Index (ODI) are useful for a quick, comprehensive and comparable evaluation of spondylodiscitis treatment. While it is known that even after successful surgical treatment, the QoL of spondylodiscitis patients remains below that of the general population, risk factors for a poor outcome have not been described so far. We did a retrospective post-hoc analysis of 130 surgically treated spondylodiscitis patients from 2008 to 2022. Biographical, clinical und QoL data were prospectively collected before (T0) and one year (T1) after surgery. The primary outcome was QoL at T1. Patients were grouped according to their ODI score at T1 (Group 1: ODI < 35, favorable QoL; Group 2: ODI ≥ 35, poor QoL) and analyzed for risk factors present at T0. Poor QoL at T1 occurred in 51 patients (39%). Multivariate analysis identified a higher preoperative leg pain (odds ratio: 1.2) and the presence of a malignant disease (odds ratio: 1.9) as independent preoperative risk factors for a poor QoL at T1. Spondylodiscitis patients with malignancy and/or preoperative leg pain may be at increased risk for poor QoL after surgical treatment. These results can be used to individualize patient information and provide a better assessment of prognosis before surgery. |
| format | Article |
| id | doaj-art-6bbf76fff19b446faa102db876e9d490 |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-6bbf76fff19b446faa102db876e9d4902025-02-09T12:38:04ZengNature PortfolioScientific Reports2045-23222024-11-011411610.1038/s41598-024-79828-8A post-hoc analysis of risk factors for poor quality of life after surgical treatment of spondylodiscitisKrishnan Sircar0Dorothee Jochimsen1Charlotte Meyer-Schwickerath2Norma Jung3Nikolaus Kernich4Peer Eysel5Ayla Yagdiran6Department of Orthopaedics and Trauma Surgery, University Hospital Cologne, Faculty of Medicine, University of CologneDepartment I of Internal Medicine, University Hospital Cologne, Faculty of Medicine, University of CologneDepartment I of Internal Medicine, University Hospital Cologne, Faculty of Medicine, University of CologneDepartment I of Internal Medicine, University Hospital Cologne, Faculty of Medicine, University of CologneDepartment of Orthopaedics and Trauma Surgery, University Hospital Cologne, Faculty of Medicine, University of CologneDepartment of Orthopaedics and Trauma Surgery, University Hospital Cologne, Faculty of Medicine, University of CologneDepartment of Orthopaedics and Trauma Surgery, University Hospital Cologne, Faculty of Medicine, University of CologneAbstract Patient-reported outcome measures for quality of life (QoL) like the Oswestry-Disability-Index (ODI) are useful for a quick, comprehensive and comparable evaluation of spondylodiscitis treatment. While it is known that even after successful surgical treatment, the QoL of spondylodiscitis patients remains below that of the general population, risk factors for a poor outcome have not been described so far. We did a retrospective post-hoc analysis of 130 surgically treated spondylodiscitis patients from 2008 to 2022. Biographical, clinical und QoL data were prospectively collected before (T0) and one year (T1) after surgery. The primary outcome was QoL at T1. Patients were grouped according to their ODI score at T1 (Group 1: ODI < 35, favorable QoL; Group 2: ODI ≥ 35, poor QoL) and analyzed for risk factors present at T0. Poor QoL at T1 occurred in 51 patients (39%). Multivariate analysis identified a higher preoperative leg pain (odds ratio: 1.2) and the presence of a malignant disease (odds ratio: 1.9) as independent preoperative risk factors for a poor QoL at T1. Spondylodiscitis patients with malignancy and/or preoperative leg pain may be at increased risk for poor QoL after surgical treatment. These results can be used to individualize patient information and provide a better assessment of prognosis before surgery.https://doi.org/10.1038/s41598-024-79828-8PromsSpondylodiscitisRisk factorsQuality of lifeMalignancy |
| spellingShingle | Krishnan Sircar Dorothee Jochimsen Charlotte Meyer-Schwickerath Norma Jung Nikolaus Kernich Peer Eysel Ayla Yagdiran A post-hoc analysis of risk factors for poor quality of life after surgical treatment of spondylodiscitis Scientific Reports Proms Spondylodiscitis Risk factors Quality of life Malignancy |
| title | A post-hoc analysis of risk factors for poor quality of life after surgical treatment of spondylodiscitis |
| title_full | A post-hoc analysis of risk factors for poor quality of life after surgical treatment of spondylodiscitis |
| title_fullStr | A post-hoc analysis of risk factors for poor quality of life after surgical treatment of spondylodiscitis |
| title_full_unstemmed | A post-hoc analysis of risk factors for poor quality of life after surgical treatment of spondylodiscitis |
| title_short | A post-hoc analysis of risk factors for poor quality of life after surgical treatment of spondylodiscitis |
| title_sort | post hoc analysis of risk factors for poor quality of life after surgical treatment of spondylodiscitis |
| topic | Proms Spondylodiscitis Risk factors Quality of life Malignancy |
| url | https://doi.org/10.1038/s41598-024-79828-8 |
| work_keys_str_mv | AT krishnansircar aposthocanalysisofriskfactorsforpoorqualityoflifeaftersurgicaltreatmentofspondylodiscitis AT dorotheejochimsen aposthocanalysisofriskfactorsforpoorqualityoflifeaftersurgicaltreatmentofspondylodiscitis AT charlottemeyerschwickerath aposthocanalysisofriskfactorsforpoorqualityoflifeaftersurgicaltreatmentofspondylodiscitis AT normajung aposthocanalysisofriskfactorsforpoorqualityoflifeaftersurgicaltreatmentofspondylodiscitis AT nikolauskernich aposthocanalysisofriskfactorsforpoorqualityoflifeaftersurgicaltreatmentofspondylodiscitis AT peereysel aposthocanalysisofriskfactorsforpoorqualityoflifeaftersurgicaltreatmentofspondylodiscitis AT aylayagdiran aposthocanalysisofriskfactorsforpoorqualityoflifeaftersurgicaltreatmentofspondylodiscitis AT krishnansircar posthocanalysisofriskfactorsforpoorqualityoflifeaftersurgicaltreatmentofspondylodiscitis AT dorotheejochimsen posthocanalysisofriskfactorsforpoorqualityoflifeaftersurgicaltreatmentofspondylodiscitis AT charlottemeyerschwickerath posthocanalysisofriskfactorsforpoorqualityoflifeaftersurgicaltreatmentofspondylodiscitis AT normajung posthocanalysisofriskfactorsforpoorqualityoflifeaftersurgicaltreatmentofspondylodiscitis AT nikolauskernich posthocanalysisofriskfactorsforpoorqualityoflifeaftersurgicaltreatmentofspondylodiscitis AT peereysel posthocanalysisofriskfactorsforpoorqualityoflifeaftersurgicaltreatmentofspondylodiscitis AT aylayagdiran posthocanalysisofriskfactorsforpoorqualityoflifeaftersurgicaltreatmentofspondylodiscitis |