Characteristics of the Small Bowel Lesions Detected by Capsule Endoscopy in Patients with Chronic Kidney Disease
Obscure gastrointestinal bleeding (OGIB) is one of the common complications in patients with chronic kidney disease (CKD), especially those who are on maintenance hemodialysis (HD). However, little is known about the characteristics of the small-bowel lesions in these patients, or of the factors tha...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2013/814214 |
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| author | Harunobu Kawamura Eiji Sakai Hiroki Endo Leo Taniguchi Yasuo Hata Akiko Ezuka Hajime Nagase Takaomi Kessoku Eiji Yamada Hidenori Ohkubo Takuma Higrashi Yusuke Sekino Tomoko Koide Hiroshi Iida Takashi Nonaka Hirokazu Takahashi Masahiko Inamori Shin Maeda Atsushi Nakajima |
| author_facet | Harunobu Kawamura Eiji Sakai Hiroki Endo Leo Taniguchi Yasuo Hata Akiko Ezuka Hajime Nagase Takaomi Kessoku Eiji Yamada Hidenori Ohkubo Takuma Higrashi Yusuke Sekino Tomoko Koide Hiroshi Iida Takashi Nonaka Hirokazu Takahashi Masahiko Inamori Shin Maeda Atsushi Nakajima |
| author_sort | Harunobu Kawamura |
| collection | DOAJ |
| description | Obscure gastrointestinal bleeding (OGIB) is one of the common complications in patients with chronic kidney disease (CKD), especially those who are on maintenance hemodialysis (HD). However, little is known about the characteristics of the small-bowel lesions in these patients, or of the factors that could predict the presence of such lesions. Therefore we enrolled a total of 42 CKD patients (including 19 HD patients and 23 non-HD patients), and compared the incidence of the small-bowel lesions among two groups. Furthermore, to identify predictive factors for the presence of small-bowel lesions, we performed multivariate logistic-regression-analyses. The incidence of small-bowel vascular lesions was significantly higher in CKD patients than in age-and-sex matched non-CKD patients (P<0.001). On the other hand, there was any significant difference of the incidence of small-bowel lesions between HD and non-HD patients. In CKD patients, past history of blood transfusion (OR 5.66; 95% CI 1.10–29.1, P=0.04) was identified as an independent predictor of the presence of vascular lesions, and history of low-dose aspirin use (OR 6.00; 95% CI 1.13–31.9, P=0.04) was identified as that of erosive/ulcerated lesions. This indicated that proactive CE examination would be clinically meaningful for these patients. |
| format | Article |
| id | doaj-art-6bbe75e0f657480d9d86bb7beceb6143 |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-6bbe75e0f657480d9d86bb7beceb61432025-02-03T05:43:51ZengWileyGastroenterology Research and Practice1687-61211687-630X2013-01-01201310.1155/2013/814214814214Characteristics of the Small Bowel Lesions Detected by Capsule Endoscopy in Patients with Chronic Kidney DiseaseHarunobu Kawamura0Eiji Sakai1Hiroki Endo2Leo Taniguchi3Yasuo Hata4Akiko Ezuka5Hajime Nagase6Takaomi Kessoku7Eiji Yamada8Hidenori Ohkubo9Takuma Higrashi10Yusuke Sekino11Tomoko Koide12Hiroshi Iida13Takashi Nonaka14Hirokazu Takahashi15Masahiko Inamori16Shin Maeda17Atsushi Nakajima18Gastroenterology Division, Odawara City Hospital, 46 Hisano, Odawara 250-8558, JapanGastroenterology Division, Yokohama City University School of Medicine, 3-9 Fuku-ura, Kanazawa-ku, Yokohama 236-0004, JapanGastroenterology Division, Yokohama City University School of Medicine, 3-9 Fuku-ura, Kanazawa-ku, Yokohama 236-0004, JapanGastroenterology Division, Chigasaki City Hospital, 1-15-5 Honson, Chigasaki 253-0042, JapanGastroenterology Division, Chigasaki City Hospital, 1-15-5 Honson, Chigasaki 253-0042, JapanGastroenterology Division, Yokohama Rosai Hospital, 3211 Kodukue-cho, Kohoku-ku, Yokohama 222-0036, JapanGastroenterology Division, Yokohama Rosai Hospital, 3211 Kodukue-cho, Kohoku-ku, Yokohama 222-0036, JapanGastroenterology Division, Yokohama City University School of Medicine, 3-9 Fuku-ura, Kanazawa-ku, Yokohama 236-0004, JapanGastroenterology Division, Yokohama City University School of Medicine, 3-9 Fuku-ura, Kanazawa-ku, Yokohama 236-0004, JapanGastroenterology Division, Yokohama City University School of Medicine, 3-9 Fuku-ura, Kanazawa-ku, Yokohama 236-0004, JapanGastroenterology Division, Yokohama City University School of Medicine, 3-9 Fuku-ura, Kanazawa-ku, Yokohama 236-0004, JapanGastroenterology Division, Yokohama City University School of Medicine, 3-9 Fuku-ura, Kanazawa-ku, Yokohama 236-0004, JapanGastroenterology Division, Yokohama City University School of Medicine, 3-9 Fuku-ura, Kanazawa-ku, Yokohama 236-0004, JapanGastroenterology Division, Yokohama City University School of Medicine, 3-9 Fuku-ura, Kanazawa-ku, Yokohama 236-0004, JapanGastroenterology Division, Yokohama City University School of Medicine, 3-9 Fuku-ura, Kanazawa-ku, Yokohama 236-0004, JapanGastroenterology Division, Yokohama City University School of Medicine, 3-9 Fuku-ura, Kanazawa-ku, Yokohama 236-0004, JapanGastroenterology Division, Yokohama City University School of Medicine, 3-9 Fuku-ura, Kanazawa-ku, Yokohama 236-0004, JapanGastroenterology Division, Yokohama City University School of Medicine, 3-9 Fuku-ura, Kanazawa-ku, Yokohama 236-0004, JapanGastroenterology Division, Yokohama City University School of Medicine, 3-9 Fuku-ura, Kanazawa-ku, Yokohama 236-0004, JapanObscure gastrointestinal bleeding (OGIB) is one of the common complications in patients with chronic kidney disease (CKD), especially those who are on maintenance hemodialysis (HD). However, little is known about the characteristics of the small-bowel lesions in these patients, or of the factors that could predict the presence of such lesions. Therefore we enrolled a total of 42 CKD patients (including 19 HD patients and 23 non-HD patients), and compared the incidence of the small-bowel lesions among two groups. Furthermore, to identify predictive factors for the presence of small-bowel lesions, we performed multivariate logistic-regression-analyses. The incidence of small-bowel vascular lesions was significantly higher in CKD patients than in age-and-sex matched non-CKD patients (P<0.001). On the other hand, there was any significant difference of the incidence of small-bowel lesions between HD and non-HD patients. In CKD patients, past history of blood transfusion (OR 5.66; 95% CI 1.10–29.1, P=0.04) was identified as an independent predictor of the presence of vascular lesions, and history of low-dose aspirin use (OR 6.00; 95% CI 1.13–31.9, P=0.04) was identified as that of erosive/ulcerated lesions. This indicated that proactive CE examination would be clinically meaningful for these patients.http://dx.doi.org/10.1155/2013/814214 |
| spellingShingle | Harunobu Kawamura Eiji Sakai Hiroki Endo Leo Taniguchi Yasuo Hata Akiko Ezuka Hajime Nagase Takaomi Kessoku Eiji Yamada Hidenori Ohkubo Takuma Higrashi Yusuke Sekino Tomoko Koide Hiroshi Iida Takashi Nonaka Hirokazu Takahashi Masahiko Inamori Shin Maeda Atsushi Nakajima Characteristics of the Small Bowel Lesions Detected by Capsule Endoscopy in Patients with Chronic Kidney Disease Gastroenterology Research and Practice |
| title | Characteristics of the Small Bowel Lesions Detected by Capsule Endoscopy in Patients with Chronic Kidney Disease |
| title_full | Characteristics of the Small Bowel Lesions Detected by Capsule Endoscopy in Patients with Chronic Kidney Disease |
| title_fullStr | Characteristics of the Small Bowel Lesions Detected by Capsule Endoscopy in Patients with Chronic Kidney Disease |
| title_full_unstemmed | Characteristics of the Small Bowel Lesions Detected by Capsule Endoscopy in Patients with Chronic Kidney Disease |
| title_short | Characteristics of the Small Bowel Lesions Detected by Capsule Endoscopy in Patients with Chronic Kidney Disease |
| title_sort | characteristics of the small bowel lesions detected by capsule endoscopy in patients with chronic kidney disease |
| url | http://dx.doi.org/10.1155/2013/814214 |
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