Androgenetic alopecia - just a cosmetic defect or a biomarker and risk factor for systemic diseases? - literature review
Introduction: Androgenetic alopecia (AGA) is the most common cause of hair loss. It has traditionally been considered a cosmetic defect, but a growing body of evidence suggests that it may serve as a biomarker and risk factor for systemic diseases, suggesting its potential role in early disease det...
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| Format: | Article |
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Kazimierz Wielki University
2025-07-01
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| Series: | Journal of Education, Health and Sport |
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| Online Access: | https://apcz.umk.pl/JEHS/article/view/61813 |
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| author | Dawid Suwała Natalia Pokrywka Marcelina Polak Klaudia Koryszko Paulina Hetnar Magdalena Tomala Sebastian Kiper Milena Fortuna Sławomir Toczek Katarzyna Jastrowicz-Chęć |
| author_facet | Dawid Suwała Natalia Pokrywka Marcelina Polak Klaudia Koryszko Paulina Hetnar Magdalena Tomala Sebastian Kiper Milena Fortuna Sławomir Toczek Katarzyna Jastrowicz-Chęć |
| author_sort | Dawid Suwała |
| collection | DOAJ |
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Introduction: Androgenetic alopecia (AGA) is the most common cause of hair loss. It has traditionally been considered a cosmetic defect, but a growing body of evidence suggests that it may serve as a biomarker and risk factor for systemic diseases, suggesting its potential role in early disease detection and prevention.
Purpose: The aim of this study is to review the available literature, analyze and summarize the current state of knowledge on the relationship between AGA and systemic diseases.
Materials and research methods: The article is based on an analysis of PubMed and Google Scholar research. A literature review was conducted using the following keywords and medical subject headings: androgenetic alopecia; quality of life; cardiovascular disease; hair loss; metabolic syndrome; comorbidity. The analysis included clinical trials, systematic reviews, meta-analyses.
Results: The analysis showed that patients with AGA were more likely to have cardiovascular disease, metabolic or endocrine disorders. Cases of increased risk of prostate and scalp cancers have also been described, as well as negative effects on mental health in people with AGA. These links underscore the need for an interdisciplinary approach to the patient and collaboration between the dermatologist and other specialists.
Conclusion: AGA is not only an aesthetic problem, but can act as a biomarker for systemic diseases and be a signal for further diagnosis. Therefore, screening should be considered, as well as collaboration between dermatologists and other specialists. Future research should focus on the mechanisms linking AGA to other conditions, developing screening protocols, and analyzing the age of onset of AGA as a potential risk for systemic diseases.
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| format | Article |
| id | doaj-art-6bbbd5e689364dd2aaede2aa5ab6997c |
| institution | Kabale University |
| issn | 2391-8306 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj-art-6bbbd5e689364dd2aaede2aa5ab6997c2025-08-20T03:50:54ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062025-07-018310.12775/JEHS.2025.83.61813Androgenetic alopecia - just a cosmetic defect or a biomarker and risk factor for systemic diseases? - literature reviewDawid Suwała0https://orcid.org/0009-0004-7606-7065Natalia Pokrywka1https://orcid.org/0009-0004-1593-8760Marcelina Polak2https://orcid.org/0009-0008-5987-4948Klaudia Koryszko3https://orcid.org/0009-0005-6294-8694Paulina Hetnar4https://orcid.org/0009-0005-2920-2575Magdalena Tomala5https://orcid.org/0009-0000-4236-4943Sebastian Kiper6https://orcid.org/0009-0006-4708-2121Milena Fortuna7https://orcid.org/0009-0009-5670-1926Sławomir Toczek8https://orcid.org/0009-0000-3936-7115Katarzyna Jastrowicz-Chęć9https://orcid.org/0009-0001-4820-0373Uniwersytet Medyczny w LublinieMedical University in LublinMedical University in Lublin1st Military Clinical Hospital with Polyclinic of Independent Public Health Care Unit in LublinMedical Centre in Piekary Slaskie, Limited Liability CompanyMilitary Institute of Aviation Medicine5th Military Clinical Hospital in Krakow 5th Military Clinical Hospital in Krakow 105th Borderland Military Hospital with a Clinic, Independent Public Health Care Facility in Zary5th Military Clinical Hospital in Krakow Introduction: Androgenetic alopecia (AGA) is the most common cause of hair loss. It has traditionally been considered a cosmetic defect, but a growing body of evidence suggests that it may serve as a biomarker and risk factor for systemic diseases, suggesting its potential role in early disease detection and prevention. Purpose: The aim of this study is to review the available literature, analyze and summarize the current state of knowledge on the relationship between AGA and systemic diseases. Materials and research methods: The article is based on an analysis of PubMed and Google Scholar research. A literature review was conducted using the following keywords and medical subject headings: androgenetic alopecia; quality of life; cardiovascular disease; hair loss; metabolic syndrome; comorbidity. The analysis included clinical trials, systematic reviews, meta-analyses. Results: The analysis showed that patients with AGA were more likely to have cardiovascular disease, metabolic or endocrine disorders. Cases of increased risk of prostate and scalp cancers have also been described, as well as negative effects on mental health in people with AGA. These links underscore the need for an interdisciplinary approach to the patient and collaboration between the dermatologist and other specialists. Conclusion: AGA is not only an aesthetic problem, but can act as a biomarker for systemic diseases and be a signal for further diagnosis. Therefore, screening should be considered, as well as collaboration between dermatologists and other specialists. Future research should focus on the mechanisms linking AGA to other conditions, developing screening protocols, and analyzing the age of onset of AGA as a potential risk for systemic diseases. https://apcz.umk.pl/JEHS/article/view/61813androgenetic alopeciaquality of lifecardiovascular diseasehair lossmetabolic syndromecomorbidity |
| spellingShingle | Dawid Suwała Natalia Pokrywka Marcelina Polak Klaudia Koryszko Paulina Hetnar Magdalena Tomala Sebastian Kiper Milena Fortuna Sławomir Toczek Katarzyna Jastrowicz-Chęć Androgenetic alopecia - just a cosmetic defect or a biomarker and risk factor for systemic diseases? - literature review Journal of Education, Health and Sport androgenetic alopecia quality of life cardiovascular disease hair loss metabolic syndrome comorbidity |
| title | Androgenetic alopecia - just a cosmetic defect or a biomarker and risk factor for systemic diseases? - literature review |
| title_full | Androgenetic alopecia - just a cosmetic defect or a biomarker and risk factor for systemic diseases? - literature review |
| title_fullStr | Androgenetic alopecia - just a cosmetic defect or a biomarker and risk factor for systemic diseases? - literature review |
| title_full_unstemmed | Androgenetic alopecia - just a cosmetic defect or a biomarker and risk factor for systemic diseases? - literature review |
| title_short | Androgenetic alopecia - just a cosmetic defect or a biomarker and risk factor for systemic diseases? - literature review |
| title_sort | androgenetic alopecia just a cosmetic defect or a biomarker and risk factor for systemic diseases literature review |
| topic | androgenetic alopecia quality of life cardiovascular disease hair loss metabolic syndrome comorbidity |
| url | https://apcz.umk.pl/JEHS/article/view/61813 |
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