Primary adenocarcinoma of duodenal bulb mimicking a pancreatic tumor: a case report
Duodenal bulb adenocarcinoma is a rare malignancy of the gastrointestinal tract. This cancer often presents with an insidious onset, making it challenging to diagnose early. A noteworthy case-study involved a 56 year-old-woman complaining from epigastric transfixing pain, jaundice, and overall healt...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2025-12-01
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| Series: | Future Science OA |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/20565623.2025.2456651 |
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| author | Eya Slama S. Ben Hamida S. Zaouga H. Elloumi I. Cheikh A. G. Dahak M. Missaoui A. Chelibi I. Ganzoui |
| author_facet | Eya Slama S. Ben Hamida S. Zaouga H. Elloumi I. Cheikh A. G. Dahak M. Missaoui A. Chelibi I. Ganzoui |
| author_sort | Eya Slama |
| collection | DOAJ |
| description | Duodenal bulb adenocarcinoma is a rare malignancy of the gastrointestinal tract. This cancer often presents with an insidious onset, making it challenging to diagnose early. A noteworthy case-study involved a 56 year-old-woman complaining from epigastric transfixing pain, jaundice, and overall health decline. The initial diagnosis suspected was a pancreatic tumor. An abdominal CT scan however showed no abnormality in the pancreas but revealed on the other hand an irregular, non-stenosing, heterogeneous fibrous thickening of the lower aspect of the duodenal bulb. An EGD showed a congested infiltrated area in the post-bulbar region, and Pathological exam confirmed the diagnosis of a primary adenocarcinoma of the duodenal bulb. The purpose of this article is to present the case of a primary adenocarcinoma of duodenal bulb mimicking a pancreatic tumor: a rare presentation of a rare tumor itself and to present points differentiating these two neoplasms. Diagnosis relies on a comprehensive assessment involving clinical, radiological, endoscopic, and histologic features. Integration of advanced imaging modalities, such as CT/MRI, coupled with upper gastrointestinal endoscopy, is crucial for accurate evaluation. |
| format | Article |
| id | doaj-art-6bb20dde6d7044d391282adfd93e400d |
| institution | Kabale University |
| issn | 2056-5623 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Future Science OA |
| spelling | doaj-art-6bb20dde6d7044d391282adfd93e400d2025-02-05T07:53:52ZengTaylor & Francis GroupFuture Science OA2056-56232025-12-0111110.1080/20565623.2025.2456651Primary adenocarcinoma of duodenal bulb mimicking a pancreatic tumor: a case reportEya Slama0S. Ben Hamida1S. Zaouga2H. Elloumi3I. Cheikh4A. G. Dahak5M. Missaoui6A. Chelibi7I. Ganzoui8Departement of Gastroenterology, Habib Bougatfa Hospital, Bizerte, TunisiaDepartement of Gastroenterology, Habib Bougatfa Hospital, Bizerte, TunisiaDepartement of Gastroenterology, Habib Bougatfa Hospital, Bizerte, TunisiaDepartement of Gastroenterology, Habib Bougatfa Hospital, Bizerte, TunisiaDepartement of Gastroenterology, Habib Bougatfa Hospital, Bizerte, TunisiaDepartement of Radiology, Habib Bougatfa Hospital, Bizerte, TunisiaDepartement of Radiology, Habib Bougatfa Hospital, Bizerte, TunisiaDepartement of Radiology, Habib Bougatfa Hospital, Bizerte, TunisiaDepartement of Radiology, Habib Bougatfa Hospital, Bizerte, TunisiaDuodenal bulb adenocarcinoma is a rare malignancy of the gastrointestinal tract. This cancer often presents with an insidious onset, making it challenging to diagnose early. A noteworthy case-study involved a 56 year-old-woman complaining from epigastric transfixing pain, jaundice, and overall health decline. The initial diagnosis suspected was a pancreatic tumor. An abdominal CT scan however showed no abnormality in the pancreas but revealed on the other hand an irregular, non-stenosing, heterogeneous fibrous thickening of the lower aspect of the duodenal bulb. An EGD showed a congested infiltrated area in the post-bulbar region, and Pathological exam confirmed the diagnosis of a primary adenocarcinoma of the duodenal bulb. The purpose of this article is to present the case of a primary adenocarcinoma of duodenal bulb mimicking a pancreatic tumor: a rare presentation of a rare tumor itself and to present points differentiating these two neoplasms. Diagnosis relies on a comprehensive assessment involving clinical, radiological, endoscopic, and histologic features. Integration of advanced imaging modalities, such as CT/MRI, coupled with upper gastrointestinal endoscopy, is crucial for accurate evaluation.https://www.tandfonline.com/doi/10.1080/20565623.2025.2456651Primary adenocarcinomaduodenalbulbchemotherapyduodeno-pancreatectomy |
| spellingShingle | Eya Slama S. Ben Hamida S. Zaouga H. Elloumi I. Cheikh A. G. Dahak M. Missaoui A. Chelibi I. Ganzoui Primary adenocarcinoma of duodenal bulb mimicking a pancreatic tumor: a case report Future Science OA Primary adenocarcinoma duodenal bulb chemotherapy duodeno-pancreatectomy |
| title | Primary adenocarcinoma of duodenal bulb mimicking a pancreatic tumor: a case report |
| title_full | Primary adenocarcinoma of duodenal bulb mimicking a pancreatic tumor: a case report |
| title_fullStr | Primary adenocarcinoma of duodenal bulb mimicking a pancreatic tumor: a case report |
| title_full_unstemmed | Primary adenocarcinoma of duodenal bulb mimicking a pancreatic tumor: a case report |
| title_short | Primary adenocarcinoma of duodenal bulb mimicking a pancreatic tumor: a case report |
| title_sort | primary adenocarcinoma of duodenal bulb mimicking a pancreatic tumor a case report |
| topic | Primary adenocarcinoma duodenal bulb chemotherapy duodeno-pancreatectomy |
| url | https://www.tandfonline.com/doi/10.1080/20565623.2025.2456651 |
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