Genome Destabilization Upon Exposure to Ionizing Radiation and During Acute Blood Loss
The paper compares the currently available cytogenetic methods (chromosomal aberration test and micronuclear (MN) test) for the evaluation of the impact of stressors, by using ionizing radiation as an example. The experimental findings have led to the conclusion that the MN test shows the status of...
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| Format: | Article |
| Language: | English |
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Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
2007-02-01
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| Series: | Общая реаниматология |
| Subjects: | |
| Online Access: | https://www.reanimatology.com/rmt/article/view/1078 |
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| author | V. L. Kozhura N. V. Kondakova S. I. Zaichkina O. M. Rozanova |
| author_facet | V. L. Kozhura N. V. Kondakova S. I. Zaichkina O. M. Rozanova |
| author_sort | V. L. Kozhura |
| collection | DOAJ |
| description | The paper compares the currently available cytogenetic methods (chromosomal aberration test and micronuclear (MN) test) for the evaluation of the impact of stressors, by using ionizing radiation as an example. The experimental findings have led to the conclusion that the MN test shows the status of genome and reveals lesions upon very weak exposures. The MN test has demonstrated that hemic hypoxia and reinfusion, as other stressors, cause genetic material destabiliza-tion. |
| format | Article |
| id | doaj-art-6b7486a537da41f3ac76dfcf2086f40d |
| institution | Kabale University |
| issn | 1813-9779 2411-7110 |
| language | English |
| publishDate | 2007-02-01 |
| publisher | Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia |
| record_format | Article |
| series | Общая реаниматология |
| spelling | doaj-art-6b7486a537da41f3ac76dfcf2086f40d2025-08-20T03:43:41ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102007-02-013151110.15360/1813-9779-2007-1-5-111078Genome Destabilization Upon Exposure to Ionizing Radiation and During Acute Blood LossV. L. Kozhura0N. V. Kondakova1S. I. Zaichkina2O. M. Rozanova3Research and Training Center of Biomedical Technologies, All-Russian Institute of Medicinal and Aromatic Plants, Russian Academy of Agricultural Sciences, Moscow Research Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow RegionResearch and Training Center of Biomedical Technologies, AllRussian Institute of Medicinal and Aromatic Plants, Russian Academy of Agricultural Sciences, Moscow Research Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow RegionResearch and Training Center of Biomedical Technologies, AllRussian Institute of Medicinal and Aromatic Plants, Russian Academy of Agricultural Sciences, Moscow Research Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow RegionResearch and Training Center of Biomedical Technologies, AllRussian Institute of Medicinal and Aromatic Plants, Russian Academy of Agricultural Sciences, Moscow Research Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow RegionThe paper compares the currently available cytogenetic methods (chromosomal aberration test and micronuclear (MN) test) for the evaluation of the impact of stressors, by using ionizing radiation as an example. The experimental findings have led to the conclusion that the MN test shows the status of genome and reveals lesions upon very weak exposures. The MN test has demonstrated that hemic hypoxia and reinfusion, as other stressors, cause genetic material destabiliza-tion.https://www.reanimatology.com/rmt/article/view/1078acute blood lossionizing radiationgenome destabilizationbone marrowmicronuclear test |
| spellingShingle | V. L. Kozhura N. V. Kondakova S. I. Zaichkina O. M. Rozanova Genome Destabilization Upon Exposure to Ionizing Radiation and During Acute Blood Loss Общая реаниматология acute blood loss ionizing radiation genome destabilization bone marrow micronuclear test |
| title | Genome Destabilization Upon Exposure to Ionizing Radiation and During Acute Blood Loss |
| title_full | Genome Destabilization Upon Exposure to Ionizing Radiation and During Acute Blood Loss |
| title_fullStr | Genome Destabilization Upon Exposure to Ionizing Radiation and During Acute Blood Loss |
| title_full_unstemmed | Genome Destabilization Upon Exposure to Ionizing Radiation and During Acute Blood Loss |
| title_short | Genome Destabilization Upon Exposure to Ionizing Radiation and During Acute Blood Loss |
| title_sort | genome destabilization upon exposure to ionizing radiation and during acute blood loss |
| topic | acute blood loss ionizing radiation genome destabilization bone marrow micronuclear test |
| url | https://www.reanimatology.com/rmt/article/view/1078 |
| work_keys_str_mv | AT vlkozhura genomedestabilizationuponexposuretoionizingradiationandduringacutebloodloss AT nvkondakova genomedestabilizationuponexposuretoionizingradiationandduringacutebloodloss AT sizaichkina genomedestabilizationuponexposuretoionizingradiationandduringacutebloodloss AT omrozanova genomedestabilizationuponexposuretoionizingradiationandduringacutebloodloss |