Lessons from the PROTECT-CH COVID-19 platform trial in care homes

Lessons from the PROTECT-CH COVID-19 platform trial in care homes

Background Coronavirus disease-2019 was associated with significant mortality and morbidity in care homes in 2020–1. Repurposed antiviral drugs might reduce morbidity and mortality through reducing viral transmission, infection, replication and inflammation. We aimed to compare the safety and effica...

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Main Authors: Philip M Bath, Jonathan Ball, Matthew Boyd, Heather Gage, Matthew Glover, Maureen Godfrey, Bruce Guthrie, Jonathan Hewitt, Robert Howard, Thomas Jaki, Edmund Juszczak, Daniel Lasserson, Paul Leighton, Val Leyland, Wei Shen Lim, Pip Logan, Garry Meakin, Alan Montgomery, Reuben Ogollah, Peter Passmore, Philip Quinlan, Caroline Rick, Simon Royal, Susan D Shenkin, Clare Upton, Adam L Gordon
Format: Article
Language:English
Published: NIHR Journals Library 2025-04-01
Series:Health Technology Assessment
Subjects:
care home
ciclesonide
covid-19
prevention
nursing home
niclosamide
prophylaxis
randomised controlled trial
residential home
cluster trial
Online Access:https://doi.org/10.3310/MTRS8833
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