Recent Advances in the Structure, Extraction, and Biological Activity of <i>Sargassum fusiforme</i> Polysaccharides

<i>Sargassum fusiforme</i> polysaccharides (SFPs) are acidic polysaccharides that possess significant medicinal and commercial potential. This review aims to summarize recent advances in the structure, extraction methods, and diverse biological activities of SFPs, including their antioxi...

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Main Authors: Shun Zhang, Liang Chen, Nan Shang, Kefeng Wu, Wang Liao
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Marine Drugs
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Online Access:https://www.mdpi.com/1660-3397/23/3/98
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author Shun Zhang
Liang Chen
Nan Shang
Kefeng Wu
Wang Liao
author_facet Shun Zhang
Liang Chen
Nan Shang
Kefeng Wu
Wang Liao
author_sort Shun Zhang
collection DOAJ
description <i>Sargassum fusiforme</i> polysaccharides (SFPs) are acidic polysaccharides that possess significant medicinal and commercial potential. This review aims to summarize recent advances in the structure, extraction methods, and diverse biological activities of SFPs, including their antioxidant, antitumor, immunomodulatory, antiviral, intestinal flora-regulating, and anti-diabetic properties. The key findings reveal the complex composition of polysaccharides, highlighting alginic acid, fucoidan, and laminaran as the primary constituents, and detailing their structural features. At the same time, the characteristics as well as the advantages and disadvantages of hot water extraction, acid extraction, alkali extraction, ultrasonic extraction, microwave extraction, and enzyme extraction were systematically compared. Finally, this review concludes by emphasizing the necessity for further research to elucidate the structure–function relationships of SFPs, optimize their extraction techniques, and provide a theoretical foundation for subsequent studies.
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issn 1660-3397
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publishDate 2025-02-01
publisher MDPI AG
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series Marine Drugs
spelling doaj-art-6b68c08f37064db4b1da36d30f78b2032025-08-20T02:42:26ZengMDPI AGMarine Drugs1660-33972025-02-012339810.3390/md23030098Recent Advances in the Structure, Extraction, and Biological Activity of <i>Sargassum fusiforme</i> PolysaccharidesShun Zhang0Liang Chen1Nan Shang2Kefeng Wu3Wang Liao4Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, and Department of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing 210009, ChinaPublic Service Platform of South China Sea for R&D Marine Biomedicine Resources, The Marine Biomedical Research Institute, Guangdong Medical University, Zhanjiang 524023, ChinaCollege of Engineering, China Agricultural University, Beijing 100083, ChinaPublic Service Platform of South China Sea for R&D Marine Biomedicine Resources, The Marine Biomedical Research Institute, Guangdong Medical University, Zhanjiang 524023, ChinaKey Laboratory of Environmental Medicine and Engineering of Ministry of Education, and Department of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing 210009, China<i>Sargassum fusiforme</i> polysaccharides (SFPs) are acidic polysaccharides that possess significant medicinal and commercial potential. This review aims to summarize recent advances in the structure, extraction methods, and diverse biological activities of SFPs, including their antioxidant, antitumor, immunomodulatory, antiviral, intestinal flora-regulating, and anti-diabetic properties. The key findings reveal the complex composition of polysaccharides, highlighting alginic acid, fucoidan, and laminaran as the primary constituents, and detailing their structural features. At the same time, the characteristics as well as the advantages and disadvantages of hot water extraction, acid extraction, alkali extraction, ultrasonic extraction, microwave extraction, and enzyme extraction were systematically compared. Finally, this review concludes by emphasizing the necessity for further research to elucidate the structure–function relationships of SFPs, optimize their extraction techniques, and provide a theoretical foundation for subsequent studies.https://www.mdpi.com/1660-3397/23/3/98<i>Sargassum fusiforme</i> polysaccharidesstructureextraction methodsbiological activity
spellingShingle Shun Zhang
Liang Chen
Nan Shang
Kefeng Wu
Wang Liao
Recent Advances in the Structure, Extraction, and Biological Activity of <i>Sargassum fusiforme</i> Polysaccharides
Marine Drugs
<i>Sargassum fusiforme</i> polysaccharides
structure
extraction methods
biological activity
title Recent Advances in the Structure, Extraction, and Biological Activity of <i>Sargassum fusiforme</i> Polysaccharides
title_full Recent Advances in the Structure, Extraction, and Biological Activity of <i>Sargassum fusiforme</i> Polysaccharides
title_fullStr Recent Advances in the Structure, Extraction, and Biological Activity of <i>Sargassum fusiforme</i> Polysaccharides
title_full_unstemmed Recent Advances in the Structure, Extraction, and Biological Activity of <i>Sargassum fusiforme</i> Polysaccharides
title_short Recent Advances in the Structure, Extraction, and Biological Activity of <i>Sargassum fusiforme</i> Polysaccharides
title_sort recent advances in the structure extraction and biological activity of i sargassum fusiforme i polysaccharides
topic <i>Sargassum fusiforme</i> polysaccharides
structure
extraction methods
biological activity
url https://www.mdpi.com/1660-3397/23/3/98
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