Analysis of risk factors of poor prognosis after recanalization treatment of anterior and posterior circulation tandem lesions
Objective To analyze the prognosis and risk factors of the anterior and posterior circulation tandem lesions (TLs) patients after recanalization treatment. Methods The general and clinical data of 42 patients with TLs who received recanalization treatment in Shijiazhuang People's Hospital from...
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| Format: | Article |
| Language: | English |
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Tianjin Huanhu Hospital
2024-11-01
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| Series: | Chinese Journal of Contemporary Neurology and Neurosurgery |
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| Online Access: | http://www.cjcnn.org/index.php/cjcnn/article/view/2952 |
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| author | YANG Lei HAN Yong⁃feng ZHANG Dong⁃liang SU Xian⁃hui JIN Wen⁃cai ZHANG Xue⁃jing |
| author_facet | YANG Lei HAN Yong⁃feng ZHANG Dong⁃liang SU Xian⁃hui JIN Wen⁃cai ZHANG Xue⁃jing |
| author_sort | YANG Lei |
| collection | DOAJ |
| description | Objective To analyze the prognosis and risk factors of the anterior and posterior circulation tandem lesions (TLs) patients after recanalization treatment. Methods The general and clinical data of 42 patients with TLs who received recanalization treatment in Shijiazhuang People's Hospital from
April 2019 to August 2022 were retrospectively collected. The prognosis of 90 d after surgery was evaluated by the modified Rankin Scale (mRS). Univariate and multivariate stepwise Logistic regression analyses were used to investigated the risk factors of poor prognosis of TLs. Results According to mRS scores at the 90 d after surgery, the patients were divided into good prognosis group (mRS ≤ 2, n = 21) and poor prognosis group (mRS > 2, n = 21). The National Institutes of Health Stroke Scale (NIHSS) score at admission (Z = ⁃ 2.916, P = 0.004), time from onset to recanalization (Z = ⁃ 2.048, P = 0.041), mechanical thrombectomy times ≥ 3 (χ2 = 4.725, P = 0.030) and the proportion of hematoma type hemorrhagic transformation (χ2 = 8.400, P = 0.004) in the poor prognosis group were higher than those in good prognosis
group. Logistic regression analysis showed that high NIHSS score at admission (OR = 12.457, 95%CI: 2.066-75.120; P = 0.006), mechanical thrombectomy times ≥ 3 (OR = 9.387, 95%CI: 1.222-72.140; P = 0.031) and postoperative hemorrhagic transformation (OR = 7.237, 95%CI: 1.019-51.403; P = 0.048) wererisk factors of poor prognosis of TLs. Conclusions Anterior and posterior circulation TLs patients with lower NHISS score at admission, mechanical thrombectomy times < 3 and without postoperative hemorrhagic
transformation may have good prognosis. |
| format | Article |
| id | doaj-art-6b68bc749a0945f9ab4e999dc2b071ab |
| institution | OA Journals |
| issn | 1672-6731 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Tianjin Huanhu Hospital |
| record_format | Article |
| series | Chinese Journal of Contemporary Neurology and Neurosurgery |
| spelling | doaj-art-6b68bc749a0945f9ab4e999dc2b071ab2025-08-20T01:55:08ZengTianjin Huanhu HospitalChinese Journal of Contemporary Neurology and Neurosurgery1672-67312024-11-012411927932DOI:10.3969/j.issn.1672⁃6731.2024.11.009Analysis of risk factors of poor prognosis after recanalization treatment of anterior and posterior circulation tandem lesionsYANG Lei0HAN Yong⁃feng1ZHANG Dong⁃liang2SU Xian⁃hui3JIN Wen⁃cai4ZHANG Xue⁃jing5Department of Neurosurgery, Shijiazhuang People's Hospital, Shijiazhuang 050000, Hebei, ChinaDepartment of Neurosurgery, Shijiazhuang People's Hospital, Shijiazhuang 050000, Hebei, ChinaDepartment of Neurosurgery, Shijiazhuang People's Hospital, Shijiazhuang 050000, Hebei, ChinaDepartment of Neurosurgery, Shijiazhuang People's Hospital, Shijiazhuang 050000, Hebei, ChinaDepartment of Neurosurgery, Shijiazhuang People's Hospital, Shijiazhuang 050000, Hebei, ChinaCenter of Medical Research, Shijiazhuang People's Hospital, Shijiazhuang 050000, Hebei, China Corresponding author:Objective To analyze the prognosis and risk factors of the anterior and posterior circulation tandem lesions (TLs) patients after recanalization treatment. Methods The general and clinical data of 42 patients with TLs who received recanalization treatment in Shijiazhuang People's Hospital from April 2019 to August 2022 were retrospectively collected. The prognosis of 90 d after surgery was evaluated by the modified Rankin Scale (mRS). Univariate and multivariate stepwise Logistic regression analyses were used to investigated the risk factors of poor prognosis of TLs. Results According to mRS scores at the 90 d after surgery, the patients were divided into good prognosis group (mRS ≤ 2, n = 21) and poor prognosis group (mRS > 2, n = 21). The National Institutes of Health Stroke Scale (NIHSS) score at admission (Z = ⁃ 2.916, P = 0.004), time from onset to recanalization (Z = ⁃ 2.048, P = 0.041), mechanical thrombectomy times ≥ 3 (χ2 = 4.725, P = 0.030) and the proportion of hematoma type hemorrhagic transformation (χ2 = 8.400, P = 0.004) in the poor prognosis group were higher than those in good prognosis group. Logistic regression analysis showed that high NIHSS score at admission (OR = 12.457, 95%CI: 2.066-75.120; P = 0.006), mechanical thrombectomy times ≥ 3 (OR = 9.387, 95%CI: 1.222-72.140; P = 0.031) and postoperative hemorrhagic transformation (OR = 7.237, 95%CI: 1.019-51.403; P = 0.048) wererisk factors of poor prognosis of TLs. Conclusions Anterior and posterior circulation TLs patients with lower NHISS score at admission, mechanical thrombectomy times < 3 and without postoperative hemorrhagic transformation may have good prognosis.http://www.cjcnn.org/index.php/cjcnn/article/view/2952ischemic stroke; tandem lesions (not in mesh); recanalization treatment (not in mesh); prognosis; risk factors; logistic models |
| spellingShingle | YANG Lei HAN Yong⁃feng ZHANG Dong⁃liang SU Xian⁃hui JIN Wen⁃cai ZHANG Xue⁃jing Analysis of risk factors of poor prognosis after recanalization treatment of anterior and posterior circulation tandem lesions Chinese Journal of Contemporary Neurology and Neurosurgery ischemic stroke; tandem lesions (not in mesh); recanalization treatment (not in mesh); prognosis; risk factors; logistic models |
| title | Analysis of risk factors of poor prognosis after recanalization treatment of anterior and posterior circulation tandem lesions |
| title_full | Analysis of risk factors of poor prognosis after recanalization treatment of anterior and posterior circulation tandem lesions |
| title_fullStr | Analysis of risk factors of poor prognosis after recanalization treatment of anterior and posterior circulation tandem lesions |
| title_full_unstemmed | Analysis of risk factors of poor prognosis after recanalization treatment of anterior and posterior circulation tandem lesions |
| title_short | Analysis of risk factors of poor prognosis after recanalization treatment of anterior and posterior circulation tandem lesions |
| title_sort | analysis of risk factors of poor prognosis after recanalization treatment of anterior and posterior circulation tandem lesions |
| topic | ischemic stroke; tandem lesions (not in mesh); recanalization treatment (not in mesh); prognosis; risk factors; logistic models |
| url | http://www.cjcnn.org/index.php/cjcnn/article/view/2952 |
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