Diagnosis and treatment of obstructive sleep apnea
Obstructive sleep apnoea (OSA) is a prevalent disorder characterized by repeated episodes of partial or complete upper airway collapse during sleep, resulting in intermittent hypoxia, hypercapnia, and sleep fragmentation. Common in middle-aged and older adults, its pathogenesis is multifactorial, en...
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| Format: | Article |
| Language: | English |
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Nicolaus Copernicus University in Toruń
2025-01-01
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| Series: | Quality in Sport |
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| Online Access: | https://apcz.umk.pl/QS/article/view/56951 |
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| author | Natalia Myśliwiec Michał Pniak Paweł Miklis Maciej Mawlichanów Aleksandra Ciesielska Aleksandra Sieradzka Krzysztof Szerej Alicja Kot Marta Wojtczak Adrian Różycki |
| author_facet | Natalia Myśliwiec Michał Pniak Paweł Miklis Maciej Mawlichanów Aleksandra Ciesielska Aleksandra Sieradzka Krzysztof Szerej Alicja Kot Marta Wojtczak Adrian Różycki |
| author_sort | Natalia Myśliwiec |
| collection | DOAJ |
| description | Obstructive sleep apnoea (OSA) is a prevalent disorder characterized by repeated episodes of partial or complete upper airway collapse during sleep, resulting in intermittent hypoxia, hypercapnia, and sleep fragmentation. Common in middle-aged and older adults, its pathogenesis is multifactorial, encompassing obesity, craniofacial abnormalities, altered upper airway muscle function, pharyngeal neuropathy, and fluid redistribution to the neck. These episodes trigger sympathetic activation, oxidative stress, and systemic inflammation, contributing to daytime sleepiness, road traffic accidents, and a spectrum of cardiovascular and metabolic comorbidities such as hypertension, arrhythmias, coronary artery disease, stroke, and diabetes mellitus. The efficacy of therapy in reversing chronic sequelae remains uncertain. Continuous positive airway pressure (CPAP) is the first-line treatment in severe cases, although patient adherence varies between 60–70%. Alternative modalities, including bi-level positive airway pressure, adaptive servo-ventilation, oral appliances, and surgical interventions, may be employed. Weight reduction and combined treatment strategies hold promise but require validation in well-designed randomized controlled trials.
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| format | Article |
| id | doaj-art-6b60bd1a5ad845e882182f05344c0f24 |
| institution | Kabale University |
| issn | 2450-3118 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Nicolaus Copernicus University in Toruń |
| record_format | Article |
| series | Quality in Sport |
| spelling | doaj-art-6b60bd1a5ad845e882182f05344c0f242025-01-11T08:22:41ZengNicolaus Copernicus University in ToruńQuality in Sport2450-31182025-01-013710.12775/QS.2025.37.56951Diagnosis and treatment of obstructive sleep apneaNatalia Myśliwiec0https://orcid.org/0000-0002-4359-9899Michał Pniak1https://orcid.org/0009-0006-2982-6078Paweł Miklis2https://orcid.org/0009-0008-4578-233XMaciej Mawlichanów3https://orcid.org/0000-0002-6543-8105Aleksandra Ciesielska4https://orcid.org/0009-0000-5015-6140Aleksandra Sieradzka5https://orcid.org/0009-0004-2281-7617Krzysztof Szerej6https://orcid.org/0009-0003-7581-4965Alicja Kot7https://orcid.org/0009-0001-2999-6775Marta Wojtczak8https://orcid.org/0009-0007-0032-7520Adrian Różycki9https://orcid.org/0000-0002-9110-5443Państwowy Instytut Medyczny MSWiA w WarszawieJohn Paul II Memorial Masovia Provincial Hospital in Siedlce, Poland University Clinical Center of the Medical University of Warsaw, Poland Military Institute of Medicine, Warsaw Poland Mazovian Rehabilitation Center "STOCER" Sp. z o.o. Railway Hospital in Pruszków, Poland Medical University of Warsaw District Hospital in Sochaczew, PolandMedical University of Warsaw, PolandCounty Health Center in Otwock Sp. z o.o. Otwock, Poland Medica Plus Family Clinic Sp. z o. o., Gdańsk, Poland Obstructive sleep apnoea (OSA) is a prevalent disorder characterized by repeated episodes of partial or complete upper airway collapse during sleep, resulting in intermittent hypoxia, hypercapnia, and sleep fragmentation. Common in middle-aged and older adults, its pathogenesis is multifactorial, encompassing obesity, craniofacial abnormalities, altered upper airway muscle function, pharyngeal neuropathy, and fluid redistribution to the neck. These episodes trigger sympathetic activation, oxidative stress, and systemic inflammation, contributing to daytime sleepiness, road traffic accidents, and a spectrum of cardiovascular and metabolic comorbidities such as hypertension, arrhythmias, coronary artery disease, stroke, and diabetes mellitus. The efficacy of therapy in reversing chronic sequelae remains uncertain. Continuous positive airway pressure (CPAP) is the first-line treatment in severe cases, although patient adherence varies between 60–70%. Alternative modalities, including bi-level positive airway pressure, adaptive servo-ventilation, oral appliances, and surgical interventions, may be employed. Weight reduction and combined treatment strategies hold promise but require validation in well-designed randomized controlled trials. https://apcz.umk.pl/QS/article/view/56951Obstructive sleep apneaapneasleep disorder treatmentpolysomnography |
| spellingShingle | Natalia Myśliwiec Michał Pniak Paweł Miklis Maciej Mawlichanów Aleksandra Ciesielska Aleksandra Sieradzka Krzysztof Szerej Alicja Kot Marta Wojtczak Adrian Różycki Diagnosis and treatment of obstructive sleep apnea Quality in Sport Obstructive sleep apnea apnea sleep disorder treatment polysomnography |
| title | Diagnosis and treatment of obstructive sleep apnea |
| title_full | Diagnosis and treatment of obstructive sleep apnea |
| title_fullStr | Diagnosis and treatment of obstructive sleep apnea |
| title_full_unstemmed | Diagnosis and treatment of obstructive sleep apnea |
| title_short | Diagnosis and treatment of obstructive sleep apnea |
| title_sort | diagnosis and treatment of obstructive sleep apnea |
| topic | Obstructive sleep apnea apnea sleep disorder treatment polysomnography |
| url | https://apcz.umk.pl/QS/article/view/56951 |
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