Redo bilateral lung transplantation in a previous heart-lung transplant recipient for invasive pulmonary scedosporiosis

Redo bilateral lung transplantation in a previous heart-lung transplant recipient for invasive pulmonary scedosporiosis

Redo-bilateral lung transplant in previous heart-lung transplant is a rare operation. We describe our surgical and medical management experience with a heart-lung transplant recipient who developed chronic lung allograft dysfunction and invasive Scedosporium apiospermum infection. The patient underw...

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Main Authors: Akshay Chauhan, MBBS, Nischal Ranganath, MD, PhD, John P. Scott, MD, Paschalis Vergidis, MD, Anja C. Roden, MD, Philip J. Spencer, MD, Mauricio A. Villavicencio, MD, Richard C. Daly, MD, Sahar A. Saddoughi, MD, PhD
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:JHLT Open
Subjects:
CLAD
heart-lung transplant
olorofim
redo-lung transplant
Scedosporium pulmonary infection
Online Access:http://www.sciencedirect.com/science/article/pii/S2950133425000424
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Summary:Redo-bilateral lung transplant in previous heart-lung transplant is a rare operation. We describe our surgical and medical management experience with a heart-lung transplant recipient who developed chronic lung allograft dysfunction and invasive Scedosporium apiospermum infection. The patient underwent a redo-bilateral lung transplant followed by a combination of inhaled voriconazole, caspofungin, and olorofim for a prolonged period. We observed no issues with bronchial anastomosis healing, and the patient is doing well on 1-year follow-up. This report outlines a successful management approach to this rare complication of heart-lung transplant recipients.
ISSN:2950-1334

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