Protection of hepatocytes from cytotoxic T cell mediated killing by interferon-alpha.

Protection of hepatocytes from cytotoxic T cell mediated killing by interferon-alpha.

<h4>Background</h4>Cellular immunity plays a key role in determining the outcome of hepatitis C virus (HCV) infection, although the majority of infections become persistent. The mechanisms behind persistence are still not clear; however, the primary site of infection, the liver, may be c...

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Main Authors: Christian B Willberg, Scott M Ward, Reginald F Clayton, Nikolai V Naoumov, Christopher McCormick, Sandra Proto, Mark Harris, Arvind H Patel, Paul Klenerman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-08-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0000791&type=printable
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