Cardiac Sympathetic Denervation as a Treatment for Ventricular Arrhythmias Refractory to Conventional Treatment: A Case Series

Background: Ventricular arrhythmias are a leading cause of sudden death. The objective of this study was to characterise the results of patients with ventricular arrhythmias refractory to standard medical management, undergoing Video-assisted thoracoscopic cardiac sympathetic denervation (VAT-CSD) d...

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Main Authors: Carolina Álvarez-Ortega, Josué Daniel Gómez-Martínez, María Alejandra Cardona-Gallardo, Nicolás Felipe Torres-España, Luis Fernando Pava-Molano, Álvaro Ignacio Sánchez-Ortiz, Mauricio Velásquez-Galvis
Format: Article
Language:English
Published: Radcliffe Medical Media 2024-05-01
Series:Interventional Cardiology: Reviews, Research, Resources
Online Access:https://www.icrjournal.com/articleindex/icr.2023.09
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author Carolina Álvarez-Ortega
Josué Daniel Gómez-Martínez
María Alejandra Cardona-Gallardo
Nicolás Felipe Torres-España
Luis Fernando Pava-Molano
Álvaro Ignacio Sánchez-Ortiz
Mauricio Velásquez-Galvis
author_facet Carolina Álvarez-Ortega
Josué Daniel Gómez-Martínez
María Alejandra Cardona-Gallardo
Nicolás Felipe Torres-España
Luis Fernando Pava-Molano
Álvaro Ignacio Sánchez-Ortiz
Mauricio Velásquez-Galvis
author_sort Carolina Álvarez-Ortega
collection DOAJ
description Background: Ventricular arrhythmias are a leading cause of sudden death. The objective of this study was to characterise the results of patients with ventricular arrhythmias refractory to standard medical management, undergoing Video-assisted thoracoscopic cardiac sympathetic denervation (VAT-CSD) during 2012–2022 in Cali, Colombia. Methods: This was an observational retrospective study, using the Institutional General Thoracic Surgery Database for patient identification and retrospectively reviewing the clinical charts for data description and analysis. Results: Clinical records of 19 patients who underwent VAT-CSD for ventricular arrhythmia were analysed. The patients were predominantly male (73.7%) with an mean age of 62 years. Ischaemic heart disease was the main underlying condition (52.6%); all individuals had a diagnosis of heart failure, with comorbidities such as hypertension (63.1%), acute MI (57.8%) and diabetes (26.3%) also present. The procedure was performed bilaterally in 89.4% of cases and was successful with minimal perioperative complications. Postoperative follow-up showed improvement in symptoms, including a significant reduction in the number of ICD shocks and emergency department visits. Conclusion: VAT-CSD is a viable, safe and palliative therapeutic option for patients with ventricular arrhythmias who have not responded to conventional treatments, achieving a significant decrease in symptoms with low mortality and perioperative complications.
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series Interventional Cardiology: Reviews, Research, Resources
spelling doaj-art-6b4790c2b46a46cea39c0c236fe7e1cc2025-08-20T02:37:51ZengRadcliffe Medical MediaInterventional Cardiology: Reviews, Research, Resources1756-14771756-14852024-05-011910.15420/icr.2023.09Cardiac Sympathetic Denervation as a Treatment for Ventricular Arrhythmias Refractory to Conventional Treatment: A Case SeriesCarolina Álvarez-Ortega0Josué Daniel Gómez-Martínez1María Alejandra Cardona-Gallardo2Nicolás Felipe Torres-España3Luis Fernando Pava-Molano4Álvaro Ignacio Sánchez-Ortiz5Mauricio Velásquez-Galvis6Fundación Valle del Lili, Centro de Investigaciones Clínicas, Cali, ColombiaFundación Valle del Lili, Centro de Investigaciones Clínicas, Cali, ColombiaUniversidad Icesi, Facultad de Ciencias de la Salud, Cali, ColombiaFundación Valle del Lili, Departamento de Cirugía, Cali, ColombiaFundación Valle del Lili, Departamento de Cardiología y Electrofisiología, Cali, ColombiaFundación Valle del Lili, Departamento de Cirugía, División de Cirugía de Tórax, Cali, ColombiaFundación Valle del Lili, Departamento de Cirugía, División de Cirugía de Tórax, Cali, ColombiaBackground: Ventricular arrhythmias are a leading cause of sudden death. The objective of this study was to characterise the results of patients with ventricular arrhythmias refractory to standard medical management, undergoing Video-assisted thoracoscopic cardiac sympathetic denervation (VAT-CSD) during 2012–2022 in Cali, Colombia. Methods: This was an observational retrospective study, using the Institutional General Thoracic Surgery Database for patient identification and retrospectively reviewing the clinical charts for data description and analysis. Results: Clinical records of 19 patients who underwent VAT-CSD for ventricular arrhythmia were analysed. The patients were predominantly male (73.7%) with an mean age of 62 years. Ischaemic heart disease was the main underlying condition (52.6%); all individuals had a diagnosis of heart failure, with comorbidities such as hypertension (63.1%), acute MI (57.8%) and diabetes (26.3%) also present. The procedure was performed bilaterally in 89.4% of cases and was successful with minimal perioperative complications. Postoperative follow-up showed improvement in symptoms, including a significant reduction in the number of ICD shocks and emergency department visits. Conclusion: VAT-CSD is a viable, safe and palliative therapeutic option for patients with ventricular arrhythmias who have not responded to conventional treatments, achieving a significant decrease in symptoms with low mortality and perioperative complications.https://www.icrjournal.com/articleindex/icr.2023.09
spellingShingle Carolina Álvarez-Ortega
Josué Daniel Gómez-Martínez
María Alejandra Cardona-Gallardo
Nicolás Felipe Torres-España
Luis Fernando Pava-Molano
Álvaro Ignacio Sánchez-Ortiz
Mauricio Velásquez-Galvis
Cardiac Sympathetic Denervation as a Treatment for Ventricular Arrhythmias Refractory to Conventional Treatment: A Case Series
Interventional Cardiology: Reviews, Research, Resources
title Cardiac Sympathetic Denervation as a Treatment for Ventricular Arrhythmias Refractory to Conventional Treatment: A Case Series
title_full Cardiac Sympathetic Denervation as a Treatment for Ventricular Arrhythmias Refractory to Conventional Treatment: A Case Series
title_fullStr Cardiac Sympathetic Denervation as a Treatment for Ventricular Arrhythmias Refractory to Conventional Treatment: A Case Series
title_full_unstemmed Cardiac Sympathetic Denervation as a Treatment for Ventricular Arrhythmias Refractory to Conventional Treatment: A Case Series
title_short Cardiac Sympathetic Denervation as a Treatment for Ventricular Arrhythmias Refractory to Conventional Treatment: A Case Series
title_sort cardiac sympathetic denervation as a treatment for ventricular arrhythmias refractory to conventional treatment a case series
url https://www.icrjournal.com/articleindex/icr.2023.09
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