Bilateral Total Hip and Right Knee Arthroplasty in a Sickle Cell Disease Patient with Multiple Joint Osteonecrosis: A Case Report and Literature Review

Sickle cell disease is an autosomal recessive genetic disorder with the underlying pathology, resulting in sickling of the red blood cells in deoxygenated conditions. Osteonecrosis is a common orthopaedic manifestation of sickle cell disease, and total joint arthroplasty is the preferred option in m...

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Main Authors: Michael Ebiyon Ugbeye, Kehinde Adesola Alatishe, Chukwuebuka Okezie
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Nigerian Postgraduate Medical Journal
Subjects:
Online Access:https://journals.lww.com/10.4103/npmj.npmj_237_24
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author Michael Ebiyon Ugbeye
Kehinde Adesola Alatishe
Chukwuebuka Okezie
author_facet Michael Ebiyon Ugbeye
Kehinde Adesola Alatishe
Chukwuebuka Okezie
author_sort Michael Ebiyon Ugbeye
collection DOAJ
description Sickle cell disease is an autosomal recessive genetic disorder with the underlying pathology, resulting in sickling of the red blood cells in deoxygenated conditions. Osteonecrosis is a common orthopaedic manifestation of sickle cell disease, and total joint arthroplasty is the preferred option in managing patients with advanced disease. This article describes bilateral total hip arthroplasty and right total knee arthroplasty (TKA) in a 41-year-old woman, a known haemoglobin SS (HBSS) patient who presented to the outpatient clinic of National Orthopaedic Hospital, Igbobi, Lagos, with recurrent bilateral hip and right knee pain of 10-year duration, with associated stiffness, valgus deformity in the knee and severe limitation of function. She had sequential bilateral total hip replacement and right TKA. She had significant improvement in function in the follow-up period. The effectiveness of total hip and knee arthroplasties in HBSS patients with osteonecrosis is well demonstrated in this article.
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institution Kabale University
issn 1117-1936
2468-6875
language English
publishDate 2024-12-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Nigerian Postgraduate Medical Journal
spelling doaj-art-6b476ae8661d43ec9a83ca712db1598f2025-01-07T09:47:56ZengWolters Kluwer Medknow PublicationsNigerian Postgraduate Medical Journal1117-19362468-68752024-12-0131434134510.4103/npmj.npmj_237_24Bilateral Total Hip and Right Knee Arthroplasty in a Sickle Cell Disease Patient with Multiple Joint Osteonecrosis: A Case Report and Literature ReviewMichael Ebiyon UgbeyeKehinde Adesola AlatisheChukwuebuka OkezieSickle cell disease is an autosomal recessive genetic disorder with the underlying pathology, resulting in sickling of the red blood cells in deoxygenated conditions. Osteonecrosis is a common orthopaedic manifestation of sickle cell disease, and total joint arthroplasty is the preferred option in managing patients with advanced disease. This article describes bilateral total hip arthroplasty and right total knee arthroplasty (TKA) in a 41-year-old woman, a known haemoglobin SS (HBSS) patient who presented to the outpatient clinic of National Orthopaedic Hospital, Igbobi, Lagos, with recurrent bilateral hip and right knee pain of 10-year duration, with associated stiffness, valgus deformity in the knee and severe limitation of function. She had sequential bilateral total hip replacement and right TKA. She had significant improvement in function in the follow-up period. The effectiveness of total hip and knee arthroplasties in HBSS patients with osteonecrosis is well demonstrated in this article.https://journals.lww.com/10.4103/npmj.npmj_237_24total hip arthroplastytotal knee arthroplastyosteoarthritisosteonecrosissickle cell disease
spellingShingle Michael Ebiyon Ugbeye
Kehinde Adesola Alatishe
Chukwuebuka Okezie
Bilateral Total Hip and Right Knee Arthroplasty in a Sickle Cell Disease Patient with Multiple Joint Osteonecrosis: A Case Report and Literature Review
Nigerian Postgraduate Medical Journal
total hip arthroplasty
total knee arthroplasty
osteoarthritis
osteonecrosis
sickle cell disease
title Bilateral Total Hip and Right Knee Arthroplasty in a Sickle Cell Disease Patient with Multiple Joint Osteonecrosis: A Case Report and Literature Review
title_full Bilateral Total Hip and Right Knee Arthroplasty in a Sickle Cell Disease Patient with Multiple Joint Osteonecrosis: A Case Report and Literature Review
title_fullStr Bilateral Total Hip and Right Knee Arthroplasty in a Sickle Cell Disease Patient with Multiple Joint Osteonecrosis: A Case Report and Literature Review
title_full_unstemmed Bilateral Total Hip and Right Knee Arthroplasty in a Sickle Cell Disease Patient with Multiple Joint Osteonecrosis: A Case Report and Literature Review
title_short Bilateral Total Hip and Right Knee Arthroplasty in a Sickle Cell Disease Patient with Multiple Joint Osteonecrosis: A Case Report and Literature Review
title_sort bilateral total hip and right knee arthroplasty in a sickle cell disease patient with multiple joint osteonecrosis a case report and literature review
topic total hip arthroplasty
total knee arthroplasty
osteoarthritis
osteonecrosis
sickle cell disease
url https://journals.lww.com/10.4103/npmj.npmj_237_24
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AT chukwuebukaokezie bilateraltotalhipandrightkneearthroplastyinasicklecelldiseasepatientwithmultiplejointosteonecrosisacasereportandliteraturereview