Sertraline-Induced Mood and Behavioral Activation in Two Adults With Prader–Willi Syndrome

Conclusion: Sertraline and other SSRI medications can cause MBA in patients with PWS at typical starting doses, although risk for adverse effects increases with higher doses. Age is a contributing factor. Knowing the genetic subtype of PWS is essential for making clinical decisions about pharmacothe...

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Main Author: Janice Forster
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Case Reports in Psychiatry
Online Access:http://dx.doi.org/10.1155/crps/9811985
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author Janice Forster
author_facet Janice Forster
author_sort Janice Forster
collection DOAJ
description Conclusion: Sertraline and other SSRI medications can cause MBA in patients with PWS at typical starting doses, although risk for adverse effects increases with higher doses. Age is a contributing factor. Knowing the genetic subtype of PWS is essential for making clinical decisions about pharmacotherapy, and results of pharmacogenomic testing may inform the selection of medication, dose, and schedule of administration.
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spelling doaj-art-6b455aa4811642c69d5a735912554f9e2025-08-20T03:11:17ZengWileyCase Reports in Psychiatry2090-68382025-01-01202510.1155/crps/9811985Sertraline-Induced Mood and Behavioral Activation in Two Adults With Prader–Willi SyndromeJanice Forster0Pittsburgh PartnershipConclusion: Sertraline and other SSRI medications can cause MBA in patients with PWS at typical starting doses, although risk for adverse effects increases with higher doses. Age is a contributing factor. Knowing the genetic subtype of PWS is essential for making clinical decisions about pharmacotherapy, and results of pharmacogenomic testing may inform the selection of medication, dose, and schedule of administration.http://dx.doi.org/10.1155/crps/9811985
spellingShingle Janice Forster
Sertraline-Induced Mood and Behavioral Activation in Two Adults With Prader–Willi Syndrome
Case Reports in Psychiatry
title Sertraline-Induced Mood and Behavioral Activation in Two Adults With Prader–Willi Syndrome
title_full Sertraline-Induced Mood and Behavioral Activation in Two Adults With Prader–Willi Syndrome
title_fullStr Sertraline-Induced Mood and Behavioral Activation in Two Adults With Prader–Willi Syndrome
title_full_unstemmed Sertraline-Induced Mood and Behavioral Activation in Two Adults With Prader–Willi Syndrome
title_short Sertraline-Induced Mood and Behavioral Activation in Two Adults With Prader–Willi Syndrome
title_sort sertraline induced mood and behavioral activation in two adults with prader willi syndrome
url http://dx.doi.org/10.1155/crps/9811985
work_keys_str_mv AT janiceforster sertralineinducedmoodandbehavioralactivationintwoadultswithpraderwillisyndrome