SUMOylation substrate encoding genes as prognostic biomarkers in pancreatic ductal adenocarcinoma with functional assessment of SAF-B2

SUMOylation substrate encoding genes as prognostic biomarkers in pancreatic ductal adenocarcinoma with functional assessment of SAF-B2

BackgroundPancreatic ductal adenocarcinoma (PDAC) is highly malignant with a poor prognosis, posing significant clinical challenges. SUMOylation, a reversible post-translational modification, plays a critical role in tumor progression, yet its prognostic significance in PDAC remains unclear.MethodsW...

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Bibliographic Details
Main Authors: Xiangjun Wang, Chuanxin Yang, Yangming Liu, Jian Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Pharmacology
Subjects:
Pancreatic ductal adenocarcinoma
SUMOylation
TAK-981
Prognosis
SAFB2
Wnt/β-Catenin signaling pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1532658/full
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