Mathematical modeling of physiological parameters in traumatic shock caused by lower limb blast injury

The aim of this study was to apply integrative physiological mathematical models to simulate physiological parameters in traumatic shock caused by lower limb blast injury.Materials and methods. At the first stage of mathematical modeling, we applied lumped parameter integrative physiological models,...

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Main Authors: I. V. Tolmachev, A. V. Anisin, A. M. Bala, D. A. Vrazhnov, A. V. Shapovalov, M. Yu. Kotlovskiy, V. V. Laptev, K. S. Brazovskiy
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2024-01-01
Series:Бюллетень сибирской медицины
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Online Access:https://bulletin.ssmu.ru/jour/article/view/5428
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author I. V. Tolmachev
A. V. Anisin
A. M. Bala
D. A. Vrazhnov
A. V. Shapovalov
M. Yu. Kotlovskiy
V. V. Laptev
K. S. Brazovskiy
author_facet I. V. Tolmachev
A. V. Anisin
A. M. Bala
D. A. Vrazhnov
A. V. Shapovalov
M. Yu. Kotlovskiy
V. V. Laptev
K. S. Brazovskiy
author_sort I. V. Tolmachev
collection DOAJ
description The aim of this study was to apply integrative physiological mathematical models to simulate physiological parameters in traumatic shock caused by lower limb blast injury.Materials and methods. At the first stage of mathematical modeling, we applied lumped parameter integrative physiological models, and at the second stage we used neural networks.Results. We developed a clinical decision support system that allows to determine the intensity of blood loss in lower limb blast injuries according to physiological monitoring data.Conclusion. The developed approaches make it possible to partially solve the problem associated with the impossibility of accumulating a sufficient amount of medical data for a specific person to create an adequate personalized clinical decision support system.
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id doaj-art-6b3f4186b06e4659a1efe0f66e664e63
institution Kabale University
issn 1682-0363
1819-3684
language English
publishDate 2024-01-01
publisher Siberian State Medical University (Tomsk)
record_format Article
series Бюллетень сибирской медицины
spelling doaj-art-6b3f4186b06e4659a1efe0f66e664e632025-08-20T03:37:46ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842024-01-0122412212910.20538/1682-0363-2023-4-122-1293037Mathematical modeling of physiological parameters in traumatic shock caused by lower limb blast injuryI. V. Tolmachev0A. V. Anisin1A. M. Bala2D. A. Vrazhnov3A. V. Shapovalov4M. Yu. Kotlovskiy5V. V. Laptev6K. S. Brazovskiy7Siberian State Medical University; Federal Research Institute for Healthcare Organization and InformatizationS.M. Kirov Military Medical AcademyS.M. Kirov Military Medical AcademySiberian State Medical UniversitySiberian State Medical UniversityFederal Research Institute for Healthcare Organization and InformatizationNational Research Tomsk Polytechnic UniversitySiberian State Medical University; National Research Tomsk Polytechnic UniversityThe aim of this study was to apply integrative physiological mathematical models to simulate physiological parameters in traumatic shock caused by lower limb blast injury.Materials and methods. At the first stage of mathematical modeling, we applied lumped parameter integrative physiological models, and at the second stage we used neural networks.Results. We developed a clinical decision support system that allows to determine the intensity of blood loss in lower limb blast injuries according to physiological monitoring data.Conclusion. The developed approaches make it possible to partially solve the problem associated with the impossibility of accumulating a sufficient amount of medical data for a specific person to create an adequate personalized clinical decision support system.https://bulletin.ssmu.ru/jour/article/view/5428mathematical modelingtraumatic shockbleedingclinical decision support systems
spellingShingle I. V. Tolmachev
A. V. Anisin
A. M. Bala
D. A. Vrazhnov
A. V. Shapovalov
M. Yu. Kotlovskiy
V. V. Laptev
K. S. Brazovskiy
Mathematical modeling of physiological parameters in traumatic shock caused by lower limb blast injury
Бюллетень сибирской медицины
mathematical modeling
traumatic shock
bleeding
clinical decision support systems
title Mathematical modeling of physiological parameters in traumatic shock caused by lower limb blast injury
title_full Mathematical modeling of physiological parameters in traumatic shock caused by lower limb blast injury
title_fullStr Mathematical modeling of physiological parameters in traumatic shock caused by lower limb blast injury
title_full_unstemmed Mathematical modeling of physiological parameters in traumatic shock caused by lower limb blast injury
title_short Mathematical modeling of physiological parameters in traumatic shock caused by lower limb blast injury
title_sort mathematical modeling of physiological parameters in traumatic shock caused by lower limb blast injury
topic mathematical modeling
traumatic shock
bleeding
clinical decision support systems
url https://bulletin.ssmu.ru/jour/article/view/5428
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AT ambala mathematicalmodelingofphysiologicalparametersintraumaticshockcausedbylowerlimbblastinjury
AT davrazhnov mathematicalmodelingofphysiologicalparametersintraumaticshockcausedbylowerlimbblastinjury
AT avshapovalov mathematicalmodelingofphysiologicalparametersintraumaticshockcausedbylowerlimbblastinjury
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