Undifferentiated (Anaplastic) Thyroid Carcinoma: Exploring the Coexistence of Differentiated and Dedifferentiated Anaplastic Elements—Critical Insights from a Case Series and Review of Literature
Undifferentiated (anaplastic) thyroid carcinoma (ATC) is a rare thyroid malignancy, constituting <2% of all thyroid carcinomas. It is an aggressive tumor, manifesting as a rapidly growing neck mass with compressive symptoms. Given that ATC often arises from dedifferentiation of well-differentiate...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Thieme Medical and Scientific Publishers Pvt. Ltd.
|
| Series: | Indian Journal of Medical and Paediatric Oncology |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1791963 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | Undifferentiated (anaplastic) thyroid carcinoma (ATC) is a rare thyroid malignancy, constituting <2% of all thyroid carcinomas. It is an aggressive tumor, manifesting as a rapidly growing neck mass with compressive symptoms. Given that ATC often arises from dedifferentiation of well-differentiated thyroid carcinoma (WDTC), it is also possible that WDTC and ATC elements coexist, necessitating a clear distinction between WDTC with anaplastic transformation and pure ATC, due to significant differences in prognosis and treatment. Emphasizing the significance of cytological evaluation, particularly with the assistance of fine-needle aspiration, we present three cases that underscore the importance of timely detection for achieving precise diagnoses and guiding subsequent management decisions. |
|---|---|
| ISSN: | 0971-5851 0975-2129 |