Immunoregulatory Role of HLA-G in Allergic Diseases
Allergic diseases are sustained by a T-helper 2 polarization leading to interleukin-4 secretion, IgE-dependent inflammation, and mast cell and eosinophil activation. HLA-G molecules, both in membrane-bound and in soluble forms, play a central role in modulation of immune responses. Elevated levels o...
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| Main Authors: | Giuseppe Murdaca, Paola Contini, Simone Negrini, Giorgio Ciprandi, Francesco Puppo |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2016-01-01
|
| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2016/6865758 |
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