Amarogentin Displays Immunomodulatory Effects in Human Mast Cells and Keratinocytes
Keratinocytes express the bitter taste receptors TAS2R1 and TAS2R38. Amarogentin as an agonist for TAS2R1 and other TAS2Rs promotes keratinocyte differentiation. Similarly, mast cells are known to express bitter taste receptors. The aim of this study was to assess whether bitter compounds display im...
Saved in:
Main Authors: | Ute Wölfle, Birgit Haarhaus, Christoph M. Schempp |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2015-01-01
|
Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2015/630128 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Toll-like receptor 2/6-stimulated HMC-1 mast cells promote keratinocyte migration in wound healing.
by: Jiyun Kwon, et al.
Published: (2025-01-01) -
Amarogentin suppresses cell proliferation and EMT process through inducing ferroptosis in colorectal cancer
by: Chao Wang, et al.
Published: (2025-01-01) -
Mast Cell Interaction with Neutrophils in Human Gastric Carcinomas: Ultrastructural Observations
by: Antonio Ieni, et al.
Published: (2016-01-01) -
A Helminth-Derived Chitinase Structurally Similar to Mammalian Chitinase Displays Immunomodulatory Properties in Inflammatory Lung Disease
by: Friederike Ebner, et al.
Published: (2021-01-01) -
Human keratinocyte sensitivity towards inflammatory cytokines varies with culture time
by: G. Elliott, et al.
Published: (1992-01-01)