Can Lp(a) become the next A1C? A case for digital health management tools to overcome inertia to Lipoprotein (a) testing

Despite its known correlations with risk of cardiovascular disease, awareness and testing for Lipoprotein (a) lags that of other serological markers with estimates that less than 1% of the US population have undergone screening. Herein we outline how digital tools framed around motivational models (...

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Main Authors: Christof Wedemeyer, Martin Peters, Graham Jones
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2025.1545787/full
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author Christof Wedemeyer
Martin Peters
Graham Jones
Graham Jones
author_facet Christof Wedemeyer
Martin Peters
Graham Jones
Graham Jones
author_sort Christof Wedemeyer
collection DOAJ
description Despite its known correlations with risk of cardiovascular disease, awareness and testing for Lipoprotein (a) lags that of other serological markers with estimates that less than 1% of the US population have undergone screening. Herein we outline how digital tools framed around motivational models (COM-B and SEM), might help increase likelihood of patients seeking Lp(a) testing as part of their managed care. Furthermore, we highlight how recent trends in prescription of GLP-1 receptor antagonists are serving to motivate patients to manage biomarkers related to T2D and obesity, which are also relevant in cardiovascular disease. Capitalizing on this trend to stimulate interest in Lp(a) management could have near term consequence, and with disease modifying therapies in development ultimately improve outcomes in cardiovascular disease.
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publisher Frontiers Media S.A.
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series Frontiers in Cardiovascular Medicine
spelling doaj-art-6b20257e6a7e4903bf8ed3632589991b2025-02-10T14:22:00ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2025-02-011210.3389/fcvm.2025.15457871545787Can Lp(a) become the next A1C? A case for digital health management tools to overcome inertia to Lipoprotein (a) testingChristof Wedemeyer0Martin Peters1Graham Jones2Graham Jones3Patient Solutions & Services, Novartis Pharma AG, Basel, SwitzerlandPatient Solutions & Services, Novartis Pharma AG, Basel, SwitzerlandData Design & Clinical Innovation, Novartis Pharmaceuticals, Cambridge, MA, United StatesClinical and Translational Science Institute, Tufts University Medical Center, Boston, MA, United StatesDespite its known correlations with risk of cardiovascular disease, awareness and testing for Lipoprotein (a) lags that of other serological markers with estimates that less than 1% of the US population have undergone screening. Herein we outline how digital tools framed around motivational models (COM-B and SEM), might help increase likelihood of patients seeking Lp(a) testing as part of their managed care. Furthermore, we highlight how recent trends in prescription of GLP-1 receptor antagonists are serving to motivate patients to manage biomarkers related to T2D and obesity, which are also relevant in cardiovascular disease. Capitalizing on this trend to stimulate interest in Lp(a) management could have near term consequence, and with disease modifying therapies in development ultimately improve outcomes in cardiovascular disease.https://www.frontiersin.org/articles/10.3389/fcvm.2025.1545787/fullawarenessdigital supportpatient awarenessmotivational toolslipoprotein aprevention
spellingShingle Christof Wedemeyer
Martin Peters
Graham Jones
Graham Jones
Can Lp(a) become the next A1C? A case for digital health management tools to overcome inertia to Lipoprotein (a) testing
Frontiers in Cardiovascular Medicine
awareness
digital support
patient awareness
motivational tools
lipoprotein a
prevention
title Can Lp(a) become the next A1C? A case for digital health management tools to overcome inertia to Lipoprotein (a) testing
title_full Can Lp(a) become the next A1C? A case for digital health management tools to overcome inertia to Lipoprotein (a) testing
title_fullStr Can Lp(a) become the next A1C? A case for digital health management tools to overcome inertia to Lipoprotein (a) testing
title_full_unstemmed Can Lp(a) become the next A1C? A case for digital health management tools to overcome inertia to Lipoprotein (a) testing
title_short Can Lp(a) become the next A1C? A case for digital health management tools to overcome inertia to Lipoprotein (a) testing
title_sort can lp a become the next a1c a case for digital health management tools to overcome inertia to lipoprotein a testing
topic awareness
digital support
patient awareness
motivational tools
lipoprotein a
prevention
url https://www.frontiersin.org/articles/10.3389/fcvm.2025.1545787/full
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