Analysis of relapsed/refractory Hodgkin lymphoma treated with autologous transplantation: A single-center experience
Introduction: Hodgkin lymphoma (HL) is one of the common lymphomas with high cure rate. Aims: The aim was to study the outcome of relapsed/refractory HL treated with autologous transplantation. Objectives: The objective was to study the overall survival, overall response, and disease-free survival o...
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| Format: | Article |
| Language: | English |
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2020-01-01
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| Series: | Indian Journal of Medical and Paediatric Oncology |
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| Online Access: | http://www.ijmpo.org/article.asp?issn=0971-5851;year=2020;volume=41;issue=1;spage=23;epage=28;aulast=Kulkarni |
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| author | Vishal Kulkarni Sulav Sapkota Girish V Badarkhe B J Srinivas Radheshyam Naik |
| author_facet | Vishal Kulkarni Sulav Sapkota Girish V Badarkhe B J Srinivas Radheshyam Naik |
| author_sort | Vishal Kulkarni |
| collection | DOAJ |
| description | Introduction: Hodgkin lymphoma (HL) is one of the common lymphomas with high cure rate. Aims: The aim was to study the outcome of relapsed/refractory HL treated with autologous transplantation. Objectives: The objective was to study the overall survival, overall response, and disease-free survival of the relapsed/refractory HL after autologous transplantation. Methods: It was a retrospective study conducted over a period of 8 years in our center using computer-based database and medical records as the data source. Results: A total of 22 patients were diagnosed with relapsed/refractory HL of which majority of cases were male patients (59%) with a mean age of 29 years (range: 15–57 years) and were Stage 4A (40.9%), with nodular sclerosis (54.5%). The overall response rate was 81.8% with 9.1% complete response, 72.7% partial response, and 4.5% stable disease; the overall survival was 77.92 ± 6.65 months, and disease-free survival was 69.66 ± 8.13 months. Conclusion: Autologous stem cell transplant plays an integral role in the treatment of patients with relapsed/refractory Hodgkin lymphoma. |
| format | Article |
| id | doaj-art-6b1df784ecb6453aaaf2a0c3c5d79f01 |
| institution | DOAJ |
| issn | 0971-5851 0975-2129 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Indian Journal of Medical and Paediatric Oncology |
| spelling | doaj-art-6b1df784ecb6453aaaf2a0c3c5d79f012025-08-20T02:54:42ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Medical and Paediatric Oncology0971-58510975-21292020-01-01411232810.4103/ijmpo.ijmpo_64_19Analysis of relapsed/refractory Hodgkin lymphoma treated with autologous transplantation: A single-center experienceVishal KulkarniSulav SapkotaGirish V BadarkheB J SrinivasRadheshyam NaikIntroduction: Hodgkin lymphoma (HL) is one of the common lymphomas with high cure rate. Aims: The aim was to study the outcome of relapsed/refractory HL treated with autologous transplantation. Objectives: The objective was to study the overall survival, overall response, and disease-free survival of the relapsed/refractory HL after autologous transplantation. Methods: It was a retrospective study conducted over a period of 8 years in our center using computer-based database and medical records as the data source. Results: A total of 22 patients were diagnosed with relapsed/refractory HL of which majority of cases were male patients (59%) with a mean age of 29 years (range: 15–57 years) and were Stage 4A (40.9%), with nodular sclerosis (54.5%). The overall response rate was 81.8% with 9.1% complete response, 72.7% partial response, and 4.5% stable disease; the overall survival was 77.92 ± 6.65 months, and disease-free survival was 69.66 ± 8.13 months. Conclusion: Autologous stem cell transplant plays an integral role in the treatment of patients with relapsed/refractory Hodgkin lymphoma.http://www.ijmpo.org/article.asp?issn=0971-5851;year=2020;volume=41;issue=1;spage=23;epage=28;aulast=Kulkarniautologoushodgkinrefractoryrelapsed |
| spellingShingle | Vishal Kulkarni Sulav Sapkota Girish V Badarkhe B J Srinivas Radheshyam Naik Analysis of relapsed/refractory Hodgkin lymphoma treated with autologous transplantation: A single-center experience Indian Journal of Medical and Paediatric Oncology autologous hodgkin refractory relapsed |
| title | Analysis of relapsed/refractory Hodgkin lymphoma treated with autologous transplantation: A single-center experience |
| title_full | Analysis of relapsed/refractory Hodgkin lymphoma treated with autologous transplantation: A single-center experience |
| title_fullStr | Analysis of relapsed/refractory Hodgkin lymphoma treated with autologous transplantation: A single-center experience |
| title_full_unstemmed | Analysis of relapsed/refractory Hodgkin lymphoma treated with autologous transplantation: A single-center experience |
| title_short | Analysis of relapsed/refractory Hodgkin lymphoma treated with autologous transplantation: A single-center experience |
| title_sort | analysis of relapsed refractory hodgkin lymphoma treated with autologous transplantation a single center experience |
| topic | autologous hodgkin refractory relapsed |
| url | http://www.ijmpo.org/article.asp?issn=0971-5851;year=2020;volume=41;issue=1;spage=23;epage=28;aulast=Kulkarni |
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