Biological effects of pyropheophorbide-a as photosensitizer and prooxidant

UV-visible absorption, chemiluminescence and ESR (electron spin-resonance) were employed to investigate characteristics of pyropheophorbide-a. The results showed that pyropheophorbide-a was photosensitized and prooxidated as the way of model Ⅱ; By estimating the viability of Tn-5B1-4 cells and morta...

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Main Authors: MA Shi-cheng, YU Hai-ning, SHEN Sheng-rong
Format: Article
Language:English
Published: Zhejiang University Press 2007-11-01
Series:浙江大学学报. 农业与生命科学版
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Online Access:https://www.academax.com/doi/10.3785/1008-9209.2007.06.0641
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author MA Shi-cheng
YU Hai-ning
SHEN Sheng-rong
author_facet MA Shi-cheng
YU Hai-ning
SHEN Sheng-rong
author_sort MA Shi-cheng
collection DOAJ
description UV-visible absorption, chemiluminescence and ESR (electron spin-resonance) were employed to investigate characteristics of pyropheophorbide-a. The results showed that pyropheophorbide-a was photosensitized and prooxidated as the way of model Ⅱ; By estimating the viability of Tn-5B1-4 cells and mortality of third instar larvae of Plutella xylostella L. under illumination, it was found that pyropheophorbide-a significantly influenced on the viability of Tn-5B1-4 cells and the mortality of third instar larvae of P. xylostella L. The cell viability of Tn-5B1-4 was reduced to 6.29%, disposed with pyropheophorbide-a for 48 h with 30 min light irradiation at the concentration of 10 μmol·L<sup>-1</sup>. After fed with pyropheophorbide-a 48 h with irradiation of ultraviolet and sunlight for 1 h, the death rate of third instar larvae of P. xylostella L., was 60% and 100%, respectively, significantly different with control. It was indicated that pyropheophorbide-a is an excellent photosensitizer and prooxidant in biological applications.
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spelling doaj-art-6b18fb84da4f4c2e90386b28588f58ef2025-08-20T03:16:11ZengZhejiang University Press浙江大学学报. 农业与生命科学版1008-92092097-51552007-11-013364164510.3785/1008-9209.2007.06.064110089209Biological effects of pyropheophorbide-a as photosensitizer and prooxidantMA Shi-chengYU Hai-ningSHEN Sheng-rongUV-visible absorption, chemiluminescence and ESR (electron spin-resonance) were employed to investigate characteristics of pyropheophorbide-a. The results showed that pyropheophorbide-a was photosensitized and prooxidated as the way of model Ⅱ; By estimating the viability of Tn-5B1-4 cells and mortality of third instar larvae of Plutella xylostella L. under illumination, it was found that pyropheophorbide-a significantly influenced on the viability of Tn-5B1-4 cells and the mortality of third instar larvae of P. xylostella L. The cell viability of Tn-5B1-4 was reduced to 6.29%, disposed with pyropheophorbide-a for 48 h with 30 min light irradiation at the concentration of 10 μmol·L<sup>-1</sup>. After fed with pyropheophorbide-a 48 h with irradiation of ultraviolet and sunlight for 1 h, the death rate of third instar larvae of P. xylostella L., was 60% and 100%, respectively, significantly different with control. It was indicated that pyropheophorbide-a is an excellent photosensitizer and prooxidant in biological applications.https://www.academax.com/doi/10.3785/1008-9209.2007.06.0641pyropheophorbide-a<italic>Plutella xylostella</italic> L.Tn-5B1-4 cellphotosensitized prooxidation
spellingShingle MA Shi-cheng
YU Hai-ning
SHEN Sheng-rong
Biological effects of pyropheophorbide-a as photosensitizer and prooxidant
浙江大学学报. 农业与生命科学版
pyropheophorbide-a
<italic>Plutella xylostella</italic> L.
Tn-5B1-4 cell
photosensitized prooxidation
title Biological effects of pyropheophorbide-a as photosensitizer and prooxidant
title_full Biological effects of pyropheophorbide-a as photosensitizer and prooxidant
title_fullStr Biological effects of pyropheophorbide-a as photosensitizer and prooxidant
title_full_unstemmed Biological effects of pyropheophorbide-a as photosensitizer and prooxidant
title_short Biological effects of pyropheophorbide-a as photosensitizer and prooxidant
title_sort biological effects of pyropheophorbide a as photosensitizer and prooxidant
topic pyropheophorbide-a
<italic>Plutella xylostella</italic> L.
Tn-5B1-4 cell
photosensitized prooxidation
url https://www.academax.com/doi/10.3785/1008-9209.2007.06.0641
work_keys_str_mv AT mashicheng biologicaleffectsofpyropheophorbideaasphotosensitizerandprooxidant
AT yuhaining biologicaleffectsofpyropheophorbideaasphotosensitizerandprooxidant
AT shenshengrong biologicaleffectsofpyropheophorbideaasphotosensitizerandprooxidant