Molecular and morphological alterations in breast tissue of transgender patients undergoing dihydrotestosterone therapy.

Molecular and morphological alterations in breast tissue of transgender patients undergoing dihydrotestosterone therapy.

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Many patients undergoing gender-affirming surgery (GAS) opt for reconstructive procedures rather than total mastectomy to achieve a more masculine chest contour. The impact of dihydrotestosterone (DHT) treatment on breast tissue remains unclear. This study evaluates the morphological changes and pro...

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Bibliographic Details
Main Authors: Jinho Lee, Maryam Foroughi, Vanderlene Kung, Rabeka Ali, Saachi Parikh, Ann McMonigal, Yun Yu, Austin Nguyen, Gabriel Zangirolani, Lina Gao, Joanna Pucilowska, Ozlen Saglam
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0325034
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