Relationship of number of seizures recorded on video-EEG to surgical outcome in refractory medial temporal lobe epilepsy
INTRODUCTION: Surgical planning for refractory medial temporal lobe epilepsy (rMTLE) relies on seizure localization by ictal electroencephalography (EEG). Multiple factors impact the number of seizures recorded. We evaluated whether seizure freedom correlated to the number of seizures recorded, and...
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Thieme Revinter Publicações
2012-09-01
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| Series: | Arquivos de Neuro-Psiquiatria |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012000900009&lng=en&tlng=en |
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| author | Rup Kamal Sainju Bethany Jacobs Wolf Leonardo Bonilha Gabriel Martz |
| author_facet | Rup Kamal Sainju Bethany Jacobs Wolf Leonardo Bonilha Gabriel Martz |
| author_sort | Rup Kamal Sainju |
| collection | DOAJ |
| description | INTRODUCTION: Surgical planning for refractory medial temporal lobe epilepsy (rMTLE) relies on seizure localization by ictal electroencephalography (EEG). Multiple factors impact the number of seizures recorded. We evaluated whether seizure freedom correlated to the number of seizures recorded, and the related factors. METHODS: We collected data for 32 patients with rMTLE who underwent anterior temporal lobectomy. Primary analysis evaluated number of seizures captured as a predictor of surgical outcome. Subsequent analyses explored factors that may seizure number. RESULTS: Number of seizures recorded did not predict seizure freedom. More seizures were recorded with more days of seizure occurrence (p<0.001), seizure clusters (p<0.011) and poorly localized seizures (PLSz) (p=0.004). Regression modeling showed a trend for subjects with fewer recorded poorly localized seizures to have better surgical outcome (p=0.052). CONCLUSIONS: Total number of recorded seizures does not predict surgical outcome. Patients with more PLSz may have worse outcome. |
| format | Article |
| id | doaj-art-6b07bac2abdd4c4a806472aff3601eee |
| institution | OA Journals |
| issn | 1678-4227 |
| language | English |
| publishDate | 2012-09-01 |
| publisher | Thieme Revinter Publicações |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj-art-6b07bac2abdd4c4a806472aff3601eee2025-08-20T01:57:15ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42272012-09-0170969469910.1590/S0004-282X2012000900009S0004-282X2012000900009Relationship of number of seizures recorded on video-EEG to surgical outcome in refractory medial temporal lobe epilepsyRup Kamal Sainju0Bethany Jacobs Wolf1Leonardo Bonilha2Gabriel Martz3University of South CarolinaMUSCUniversity of South CarolinaUniversity of South CarolinaINTRODUCTION: Surgical planning for refractory medial temporal lobe epilepsy (rMTLE) relies on seizure localization by ictal electroencephalography (EEG). Multiple factors impact the number of seizures recorded. We evaluated whether seizure freedom correlated to the number of seizures recorded, and the related factors. METHODS: We collected data for 32 patients with rMTLE who underwent anterior temporal lobectomy. Primary analysis evaluated number of seizures captured as a predictor of surgical outcome. Subsequent analyses explored factors that may seizure number. RESULTS: Number of seizures recorded did not predict seizure freedom. More seizures were recorded with more days of seizure occurrence (p<0.001), seizure clusters (p<0.011) and poorly localized seizures (PLSz) (p=0.004). Regression modeling showed a trend for subjects with fewer recorded poorly localized seizures to have better surgical outcome (p=0.052). CONCLUSIONS: Total number of recorded seizures does not predict surgical outcome. Patients with more PLSz may have worse outcome.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012000900009&lng=en&tlng=enepilepsialobo temporalcirurgia de epilepsiaeletroencefalografia |
| spellingShingle | Rup Kamal Sainju Bethany Jacobs Wolf Leonardo Bonilha Gabriel Martz Relationship of number of seizures recorded on video-EEG to surgical outcome in refractory medial temporal lobe epilepsy Arquivos de Neuro-Psiquiatria epilepsia lobo temporal cirurgia de epilepsia eletroencefalografia |
| title | Relationship of number of seizures recorded on video-EEG to surgical outcome in refractory medial temporal lobe epilepsy |
| title_full | Relationship of number of seizures recorded on video-EEG to surgical outcome in refractory medial temporal lobe epilepsy |
| title_fullStr | Relationship of number of seizures recorded on video-EEG to surgical outcome in refractory medial temporal lobe epilepsy |
| title_full_unstemmed | Relationship of number of seizures recorded on video-EEG to surgical outcome in refractory medial temporal lobe epilepsy |
| title_short | Relationship of number of seizures recorded on video-EEG to surgical outcome in refractory medial temporal lobe epilepsy |
| title_sort | relationship of number of seizures recorded on video eeg to surgical outcome in refractory medial temporal lobe epilepsy |
| topic | epilepsia lobo temporal cirurgia de epilepsia eletroencefalografia |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012000900009&lng=en&tlng=en |
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