Biomarkers in molecular medicine: cancer detection and diagnosis

In spite of advances in diagnostics and therapeutics, cancer remains the second leading cause of death in the U.S. Successful cancer treatment depends not only on better therapies but also on improved methods to assess an individual's risk of developing cancer and to detect cancers at early sta...

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Main Authors: Padma Maruvada, Wendy Wang, Paul D. Wagner, Sudhir Srivastava
Format: Article
Language:English
Published: Taylor & Francis Group 2005-04-01
Series:BioTechniques
Online Access:https://www.future-science.com/doi/10.2144/05384SU04
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author Padma Maruvada
Wendy Wang
Paul D. Wagner
Sudhir Srivastava
author_facet Padma Maruvada
Wendy Wang
Paul D. Wagner
Sudhir Srivastava
author_sort Padma Maruvada
collection DOAJ
description In spite of advances in diagnostics and therapeutics, cancer remains the second leading cause of death in the U.S. Successful cancer treatment depends not only on better therapies but also on improved methods to assess an individual's risk of developing cancer and to detect cancers at early stages when they can be more effectively treated. Current cancer diagnostic imaging methods are labor-intensive and expensive, especially for screening large asymptomatic populations. Effective screening strategies depend on methods that are noninvasive and detect cancers in their early stages of development. There is increasing interest and enthusiasm in molecular markers as tools for cancer detection and prognosis. It is hoped that newly discovered cancer biomarkers and advances in high-throughput technologies would revolutionize cancer therapies by improving cancer risk assessment, early detection, diagnosis, prognosis, and monitoring therapeutic response. These biomarkers will be used either as stand-alone tests or to complement existing imaging methods.
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1940-9818
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publisher Taylor & Francis Group
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series BioTechniques
spelling doaj-art-6aeb85a4d4f5410698c163a07eaab4ba2025-08-20T02:25:54ZengTaylor & Francis GroupBioTechniques0736-62051940-98182005-04-01384SS9S1510.2144/05384SU04Biomarkers in molecular medicine: cancer detection and diagnosisPadma Maruvada0Wendy Wang1Paul D. Wagner2Sudhir Srivastava31Division of Cancer Prevention, National Cancer Institute, Bethesda, MD, USA1Division of Cancer Prevention, National Cancer Institute, Bethesda, MD, USA1Division of Cancer Prevention, National Cancer Institute, Bethesda, MD, USA1Division of Cancer Prevention, National Cancer Institute, Bethesda, MD, USAIn spite of advances in diagnostics and therapeutics, cancer remains the second leading cause of death in the U.S. Successful cancer treatment depends not only on better therapies but also on improved methods to assess an individual's risk of developing cancer and to detect cancers at early stages when they can be more effectively treated. Current cancer diagnostic imaging methods are labor-intensive and expensive, especially for screening large asymptomatic populations. Effective screening strategies depend on methods that are noninvasive and detect cancers in their early stages of development. There is increasing interest and enthusiasm in molecular markers as tools for cancer detection and prognosis. It is hoped that newly discovered cancer biomarkers and advances in high-throughput technologies would revolutionize cancer therapies by improving cancer risk assessment, early detection, diagnosis, prognosis, and monitoring therapeutic response. These biomarkers will be used either as stand-alone tests or to complement existing imaging methods.https://www.future-science.com/doi/10.2144/05384SU04
spellingShingle Padma Maruvada
Wendy Wang
Paul D. Wagner
Sudhir Srivastava
Biomarkers in molecular medicine: cancer detection and diagnosis
BioTechniques
title Biomarkers in molecular medicine: cancer detection and diagnosis
title_full Biomarkers in molecular medicine: cancer detection and diagnosis
title_fullStr Biomarkers in molecular medicine: cancer detection and diagnosis
title_full_unstemmed Biomarkers in molecular medicine: cancer detection and diagnosis
title_short Biomarkers in molecular medicine: cancer detection and diagnosis
title_sort biomarkers in molecular medicine cancer detection and diagnosis
url https://www.future-science.com/doi/10.2144/05384SU04
work_keys_str_mv AT padmamaruvada biomarkersinmolecularmedicinecancerdetectionanddiagnosis
AT wendywang biomarkersinmolecularmedicinecancerdetectionanddiagnosis
AT pauldwagner biomarkersinmolecularmedicinecancerdetectionanddiagnosis
AT sudhirsrivastava biomarkersinmolecularmedicinecancerdetectionanddiagnosis