Multiple Myeloma-Associated Kidney Disease Complicated by Sudden Death in a 68-Year-Old Man
Kidney disease can complicate multiple myeloma, and this carries a poor prognosis. The multidisciplinary management involves the use of some cardiotoxic drugs which could be fatal. We present the management of a 68-year-old man with chronic back pain, recurrent vomiting, numbness, and tingling sensa...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-07-01
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| Series: | Assam Journal of Internal Medicine |
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| Online Access: | https://journals.lww.com/10.4103/ajoim.ajoim_20_24 |
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| author | Victoria L. Ogala-Akogwu Peter K. Uduagbamen Habib Galadanci Emmanuel A. Anteyi |
| author_facet | Victoria L. Ogala-Akogwu Peter K. Uduagbamen Habib Galadanci Emmanuel A. Anteyi |
| author_sort | Victoria L. Ogala-Akogwu |
| collection | DOAJ |
| description | Kidney disease can complicate multiple myeloma, and this carries a poor prognosis. The multidisciplinary management involves the use of some cardiotoxic drugs which could be fatal. We present the management of a 68-year-old man with chronic back pain, recurrent vomiting, numbness, and tingling sensation for 4 weeks. He had proteinuria, anemia, hypercalcemia, hyperuricemia, serum and urinary paraproteins, lytic bone lesions, and bone marrow plasmacytosis. He was managed for multiple myeloma-associated kidney disease with rehydration, lenalidomide, dexamethasone, antibiotics, and hemodialysis. He became stable and continued treatment till he died suddenly in his sleep. A detailed cardiovascular assessment and drugs pharmacodynamics is essential to prevent sudden death. |
| format | Article |
| id | doaj-art-6ae7e963fcf147599276b74cadf30c41 |
| institution | DOAJ |
| issn | 2278-8239 2773-0166 |
| language | English |
| publishDate | 2024-07-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Assam Journal of Internal Medicine |
| spelling | doaj-art-6ae7e963fcf147599276b74cadf30c412025-08-20T03:10:41ZengWolters Kluwer Medknow PublicationsAssam Journal of Internal Medicine2278-82392773-01662024-07-0114212813110.4103/ajoim.ajoim_20_24Multiple Myeloma-Associated Kidney Disease Complicated by Sudden Death in a 68-Year-Old ManVictoria L. Ogala-AkogwuPeter K. UduagbamenHabib GaladanciEmmanuel A. AnteyiKidney disease can complicate multiple myeloma, and this carries a poor prognosis. The multidisciplinary management involves the use of some cardiotoxic drugs which could be fatal. We present the management of a 68-year-old man with chronic back pain, recurrent vomiting, numbness, and tingling sensation for 4 weeks. He had proteinuria, anemia, hypercalcemia, hyperuricemia, serum and urinary paraproteins, lytic bone lesions, and bone marrow plasmacytosis. He was managed for multiple myeloma-associated kidney disease with rehydration, lenalidomide, dexamethasone, antibiotics, and hemodialysis. He became stable and continued treatment till he died suddenly in his sleep. A detailed cardiovascular assessment and drugs pharmacodynamics is essential to prevent sudden death.https://journals.lww.com/10.4103/ajoim.ajoim_20_24cardiotoxicityhemodialysislenalidomidemultiple myelomaparaproteins kidney diseaseplasmacytosissudden death |
| spellingShingle | Victoria L. Ogala-Akogwu Peter K. Uduagbamen Habib Galadanci Emmanuel A. Anteyi Multiple Myeloma-Associated Kidney Disease Complicated by Sudden Death in a 68-Year-Old Man Assam Journal of Internal Medicine cardiotoxicity hemodialysis lenalidomide multiple myeloma paraproteins kidney disease plasmacytosis sudden death |
| title | Multiple Myeloma-Associated Kidney Disease Complicated by Sudden Death in a 68-Year-Old Man |
| title_full | Multiple Myeloma-Associated Kidney Disease Complicated by Sudden Death in a 68-Year-Old Man |
| title_fullStr | Multiple Myeloma-Associated Kidney Disease Complicated by Sudden Death in a 68-Year-Old Man |
| title_full_unstemmed | Multiple Myeloma-Associated Kidney Disease Complicated by Sudden Death in a 68-Year-Old Man |
| title_short | Multiple Myeloma-Associated Kidney Disease Complicated by Sudden Death in a 68-Year-Old Man |
| title_sort | multiple myeloma associated kidney disease complicated by sudden death in a 68 year old man |
| topic | cardiotoxicity hemodialysis lenalidomide multiple myeloma paraproteins kidney disease plasmacytosis sudden death |
| url | https://journals.lww.com/10.4103/ajoim.ajoim_20_24 |
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