A case of human infection with avian Influenza A/H7N9 virus in Beijing: virological and serological analysis
This study described some essential viral and sera-characteristics of A/H7N9 virus infection in a 61-year old case patient. With the antiviral therapy and respiratory support, the patient showed a significant decrease of viral loads from 6.72 log10 copies/mL to 0 in 22 days, and a correlated increas...
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| Format: | Article |
| Language: | English |
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The Journal of Infection in Developing Countries
2015-03-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/5875 |
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| author | Yang Pan Weixian Shi Peng Yang Shuangsheng Wu Xiaomin Peng Shujuan Cui Daitao Zhang Guilan Lu Jiachen Zhao Yimeng Liu Quanyi Wang |
| author_facet | Yang Pan Weixian Shi Peng Yang Shuangsheng Wu Xiaomin Peng Shujuan Cui Daitao Zhang Guilan Lu Jiachen Zhao Yimeng Liu Quanyi Wang |
| author_sort | Yang Pan |
| collection | DOAJ |
| description | This study described some essential viral and sera-characteristics of A/H7N9 virus infection in a 61-year old case patient. With the antiviral therapy and respiratory support, the patient showed a significant decrease of viral loads from 6.72 log10 copies/mL to 0 in 22 days, and a correlated increase of serum hemagglutination inhibition titers during the same period. Phylogenetic analysis demonstrated that the isolated strain was highly homologous to previous strains isolated in the southeast of China. Drug resistance-associated R292K mutation became detectable 17 days after antiviral therapy, but no remarkable influence on the viral clearance was observed.
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| format | Article |
| id | doaj-art-6adfa6dabffb41d694c935363edd7b7a |
| institution | Kabale University |
| issn | 1972-2680 |
| language | English |
| publishDate | 2015-03-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-6adfa6dabffb41d694c935363edd7b7a2025-08-20T03:48:46ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802015-03-0190310.3855/jidc.5875A case of human infection with avian Influenza A/H7N9 virus in Beijing: virological and serological analysisYang Pan0Weixian Shi1Peng Yang2Shuangsheng Wu3Xiaomin Peng4Shujuan Cui5Daitao Zhang6Guilan Lu7Jiachen Zhao8Yimeng Liu9Quanyi Wang10Institute for Infectious Disease and Endemic Disease Control, Beijing Center for Disease Prevention and Control (CDC), Beijing, ChinaInstitute for Infectious Disease and Endemic Disease Control, Beijing Center for Disease Prevention and Control (CDC), Beijing, ChinaInstitute for Infectious Disease and Endemic Disease Control, Beijing Center for Disease Prevention and Control (CDC), Beijing, ChinaInstitute for Infectious Disease and Endemic Disease Control, Beijing Center for Disease Prevention and Control (CDC), Beijing, ChinaInstitute for Infectious Disease and Endemic Disease Control, Beijing Center for Disease Prevention and Control (CDC), Beijing, ChinaInstitute for Infectious Disease and Endemic Disease Control, Beijing Center for Disease Prevention and Control (CDC), Beijing, ChinaInstitute for Infectious Disease and Endemic Disease Control, Beijing Center for Disease Prevention and Control (CDC), Beijing, ChinaInstitute for Infectious Disease and Endemic Disease Control, Beijing Center for Disease Prevention and Control (CDC), Beijing, ChinaInstitute for Infectious Disease and Endemic Disease Control, Beijing Center for Disease Prevention and Control (CDC), Beijing, ChinaInstitute for Infectious Disease and Endemic Disease Control, Beijing Center for Disease Prevention and Control (CDC), Beijing, ChinaInstitute for Infectious Disease and Endemic Disease Control, Beijing Center for Disease Prevention and Control (CDC), Beijing, ChinaThis study described some essential viral and sera-characteristics of A/H7N9 virus infection in a 61-year old case patient. With the antiviral therapy and respiratory support, the patient showed a significant decrease of viral loads from 6.72 log10 copies/mL to 0 in 22 days, and a correlated increase of serum hemagglutination inhibition titers during the same period. Phylogenetic analysis demonstrated that the isolated strain was highly homologous to previous strains isolated in the southeast of China. Drug resistance-associated R292K mutation became detectable 17 days after antiviral therapy, but no remarkable influence on the viral clearance was observed. https://jidc.org/index.php/journal/article/view/5875InfluenzaH7N9 avian influenzadrug resistanceantibodyviral load |
| spellingShingle | Yang Pan Weixian Shi Peng Yang Shuangsheng Wu Xiaomin Peng Shujuan Cui Daitao Zhang Guilan Lu Jiachen Zhao Yimeng Liu Quanyi Wang A case of human infection with avian Influenza A/H7N9 virus in Beijing: virological and serological analysis Journal of Infection in Developing Countries Influenza H7N9 avian influenza drug resistance antibody viral load |
| title | A case of human infection with avian Influenza A/H7N9 virus in Beijing: virological and serological analysis |
| title_full | A case of human infection with avian Influenza A/H7N9 virus in Beijing: virological and serological analysis |
| title_fullStr | A case of human infection with avian Influenza A/H7N9 virus in Beijing: virological and serological analysis |
| title_full_unstemmed | A case of human infection with avian Influenza A/H7N9 virus in Beijing: virological and serological analysis |
| title_short | A case of human infection with avian Influenza A/H7N9 virus in Beijing: virological and serological analysis |
| title_sort | case of human infection with avian influenza a h7n9 virus in beijing virological and serological analysis |
| topic | Influenza H7N9 avian influenza drug resistance antibody viral load |
| url | https://jidc.org/index.php/journal/article/view/5875 |
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