Chimeric SFT2D2‐TBX19 Promotes Prostate Cancer Progression by Encoding TBX19‐202 Protein and Stabilizing Mitochondrial ATP Synthase through ATP5F1A Phosphorylation

Chimeric SFT2D2‐TBX19 Promotes Prostate Cancer Progression by Encoding TBX19‐202 Protein and Stabilizing Mitochondrial ATP Synthase through ATP5F1A Phosphorylation

Abstract Specific chimeric RNAs and their products are consistently regarded as ideal tumor diagnostic markers and therapeutic targets. Chimeric RNAs can mediate tumor cell plasticity, neuroendocrine processes, polarization of tumor‐associated macrophages, and resistance to chemotherapy and immunoth...

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Main Authors: Chenxi Hu, Zaosong Zheng, Shiyu Pang, Yuanchao Zhu, Jirong Jie, Zhuocheng Lai, Xiangbo Zeng, Yongyuan Xiao, Zhifeng Chen, Jingjing Zhao, Yuejun Du, Fei Li, Qiong Wang, Wanlong Tan
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Advanced Science
Subjects:
ATP synthase
chimeric RNA
mitochondrial stability
prostate cancer
SFT2D2‐TBX19
Online Access:https://doi.org/10.1002/advs.202408426
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https://doi.org/10.1002/advs.202408426

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