Novel benzylidene derivatives: Synthesis and their antimicrobial and anticancer studies and in silico investigations

Novel benzylidene derivatives: Synthesis and their antimicrobial and anticancer studies and in silico investigations

Given the importance of carbohydrate-based drugs, this study focused on the synthesis of five novel analogs (3–7) of methyl 4,6-O-benzylidene-α-D-glucopyranoside (2, MBDG). In vitro antimicrobial screening revealed that these MBDG derivatives possess promising antifungal activity against Aspergillus...

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Bibliographic Details
Main Authors: Sarkar M.A. Kawsar, Md. Ahad Hossain, Mohammad I. Hosen, Mehul P. Parmar, Subham G. Patel, Hitendra M. Patel, Imtiaj Hasan, Suvro Biswas, Md. Abu Saleh
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Chemical Physics Impact
Subjects:
MBDG derivatives
Antimicrobial study
Anticancer study
Molecular docking
MD simulation
In silico ADMET prediction
Online Access:http://www.sciencedirect.com/science/article/pii/S266702242400330X
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