Recent advances in the pathogenesis of acute kidney injury caused by COVID-19
Severe acute respiratory syndrome coronavirus 2 （SARS-CoV-2） is a highly contagious respiratory virus. Acute kidney injury （AKI） associated with COVID-19 （coronavirus disease 2019） has been reported in a growing number of clinical cases. Some recent studies noted that kidney might be a major target...
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| Format: | Article |
| Language: | zho |
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Editorial Department of Journal of Clinical Nephrology
2022-10-01
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| Series: | Linchuang shenzangbing zazhi |
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| Online Access: | http://www.lcszb.com/thesisDetails#10.3969/j.issn.1671-2390.2022.10.012 |
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| author | Wei Kai-yue Mi Yan Wang Cai-li |
| author_facet | Wei Kai-yue Mi Yan Wang Cai-li |
| author_sort | Wei Kai-yue |
| collection | DOAJ |
| description | Severe acute respiratory syndrome coronavirus 2 （SARS-CoV-2） is a highly contagious respiratory virus. Acute kidney injury （AKI） associated with COVID-19 （coronavirus disease 2019） has been reported in a growing number of clinical cases. Some recent studies noted that kidney might be a major target organ of SARS-COV-2. Multiple factors cause the changes of renal function， including direct viral toxicity， renin-angiotensin aldosterone system imbalances， disorders of immune system， cytokine storm， rhabdomyolysis， blood coagulation dysfunction， sepsis， drug-related renal toxicity and crosstalking between organ and symptoms caused by prerenal factors. This review summarized the potential pathogenesis of COVID-19-induced AKI. |
| format | Article |
| id | doaj-art-6accf3513bcc47d2bbb5485754238f21 |
| institution | DOAJ |
| issn | 1671-2390 |
| language | zho |
| publishDate | 2022-10-01 |
| publisher | Editorial Department of Journal of Clinical Nephrology |
| record_format | Article |
| series | Linchuang shenzangbing zazhi |
| spelling | doaj-art-6accf3513bcc47d2bbb5485754238f212025-08-20T02:56:05ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902022-10-012286686931958918Recent advances in the pathogenesis of acute kidney injury caused by COVID-19Wei Kai-yueMi YanWang Cai-liSevere acute respiratory syndrome coronavirus 2 （SARS-CoV-2） is a highly contagious respiratory virus. Acute kidney injury （AKI） associated with COVID-19 （coronavirus disease 2019） has been reported in a growing number of clinical cases. Some recent studies noted that kidney might be a major target organ of SARS-COV-2. Multiple factors cause the changes of renal function， including direct viral toxicity， renin-angiotensin aldosterone system imbalances， disorders of immune system， cytokine storm， rhabdomyolysis， blood coagulation dysfunction， sepsis， drug-related renal toxicity and crosstalking between organ and symptoms caused by prerenal factors. This review summarized the potential pathogenesis of COVID-19-induced AKI.http://www.lcszb.com/thesisDetails#10.3969/j.issn.1671-2390.2022.10.012Coronavirus disease 2019Acute kidney injurySevere acute respiratory syndrome coronavirus 2Renin-angiotensin-aldosterone system |
| spellingShingle | Wei Kai-yue Mi Yan Wang Cai-li Recent advances in the pathogenesis of acute kidney injury caused by COVID-19 Linchuang shenzangbing zazhi Coronavirus disease 2019 Acute kidney injury Severe acute respiratory syndrome coronavirus 2 Renin-angiotensin-aldosterone system |
| title | Recent advances in the pathogenesis of acute kidney injury caused by COVID-19 |
| title_full | Recent advances in the pathogenesis of acute kidney injury caused by COVID-19 |
| title_fullStr | Recent advances in the pathogenesis of acute kidney injury caused by COVID-19 |
| title_full_unstemmed | Recent advances in the pathogenesis of acute kidney injury caused by COVID-19 |
| title_short | Recent advances in the pathogenesis of acute kidney injury caused by COVID-19 |
| title_sort | recent advances in the pathogenesis of acute kidney injury caused by covid 19 |
| topic | Coronavirus disease 2019 Acute kidney injury Severe acute respiratory syndrome coronavirus 2 Renin-angiotensin-aldosterone system |
| url | http://www.lcszb.com/thesisDetails#10.3969/j.issn.1671-2390.2022.10.012 |
| work_keys_str_mv | AT weikaiyue recentadvancesinthepathogenesisofacutekidneyinjurycausedbycovid19 AT miyan recentadvancesinthepathogenesisofacutekidneyinjurycausedbycovid19 AT wangcaili recentadvancesinthepathogenesisofacutekidneyinjurycausedbycovid19 |