Recent advances in the pathogenesis of acute kidney injury caused by COVID-19
Severe acute respiratory syndrome coronavirus 2 （SARS-CoV-2） is a highly contagious respiratory virus. Acute kidney injury （AKI） associated with COVID-19 （coronavirus disease 2019） has been reported in a growing number of clinical cases. Some recent studies noted that kidney might be a major target...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | zho |
| Published: |
Editorial Department of Journal of Clinical Nephrology
2022-10-01
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| Series: | Linchuang shenzangbing zazhi |
| Subjects: | |
| Online Access: | http://www.lcszb.com/thesisDetails#10.3969/j.issn.1671-2390.2022.10.012 |
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| Summary: | Severe acute respiratory syndrome coronavirus 2 （SARS-CoV-2） is a highly contagious respiratory virus. Acute kidney injury （AKI） associated with COVID-19 （coronavirus disease 2019） has been reported in a growing number of clinical cases. Some recent studies noted that kidney might be a major target organ of SARS-COV-2. Multiple factors cause the changes of renal function， including direct viral toxicity， renin-angiotensin aldosterone system imbalances， disorders of immune system， cytokine storm， rhabdomyolysis， blood coagulation dysfunction， sepsis， drug-related renal toxicity and crosstalking between organ and symptoms caused by prerenal factors. This review summarized the potential pathogenesis of COVID-19-induced AKI. |
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| ISSN: | 1671-2390 |