Systemic Immunoglobulin Light Chain Amyloidosis Presenting as Painful Penile Ulcers
Immunoglobulin light chain (AL) amyloidosis is a systemic form of amyloidosis that commonly affects the heart, kidney, liver, and nervous system. Penile involvement in AL amyloidosis is rare and thus often not considered in the differential diagnosis for penile ulcers. We report a case of an elderly...
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| Format: | Article |
| Language: | English |
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American College of Physicians
2022-09-01
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| Series: | Annals of Internal Medicine: Clinical Cases |
| Online Access: | https://www.acpjournals.org/doi/10.7326/aimcc.2022.0526 |
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| author | Crystal Lihong Yan Fireneh N. Beshah Karen Eliahu James E. Hoffman |
| author_facet | Crystal Lihong Yan Fireneh N. Beshah Karen Eliahu James E. Hoffman |
| author_sort | Crystal Lihong Yan |
| collection | DOAJ |
| description | Immunoglobulin light chain (AL) amyloidosis is a systemic form of amyloidosis that commonly affects the heart, kidney, liver, and nervous system. Penile involvement in AL amyloidosis is rare and thus often not considered in the differential diagnosis for penile ulcers. We report a case of an elderly man with nonhealing, painful penile ulcers who had AL amyloidosis with cardiac, renal, and liver involvement. His penile lesions were successfully treated with surgical resection of the amyloid deposits. Even after serologic relapse of his systemic amyloidosis, he has not had recurrence of his penile ulcers many years later. |
| format | Article |
| id | doaj-art-6ac93cf65e79417dbeb8ad91d6a0a80e |
| institution | DOAJ |
| issn | 2767-7664 |
| language | English |
| publishDate | 2022-09-01 |
| publisher | American College of Physicians |
| record_format | Article |
| series | Annals of Internal Medicine: Clinical Cases |
| spelling | doaj-art-6ac93cf65e79417dbeb8ad91d6a0a80e2025-08-20T03:18:46ZengAmerican College of PhysiciansAnnals of Internal Medicine: Clinical Cases2767-76642022-09-011710.7326/aimcc.2022.0526Systemic Immunoglobulin Light Chain Amyloidosis Presenting as Painful Penile UlcersCrystal Lihong Yan0Fireneh N. Beshah1Karen Eliahu2James E. Hoffman31Division of Internal Medicine, University of Miami/Jackson Memorial Hospital, Miami, Florida2Department of Pathology and Laboratory Medicine, University of Miami/Jackson Memorial Hospital, Miami, Florida3University of Miami Miller School of Medicine, Miami, Florida4Division of Hematology, Sylvester Comprehensive Care Center, Miami, FloridaImmunoglobulin light chain (AL) amyloidosis is a systemic form of amyloidosis that commonly affects the heart, kidney, liver, and nervous system. Penile involvement in AL amyloidosis is rare and thus often not considered in the differential diagnosis for penile ulcers. We report a case of an elderly man with nonhealing, painful penile ulcers who had AL amyloidosis with cardiac, renal, and liver involvement. His penile lesions were successfully treated with surgical resection of the amyloid deposits. Even after serologic relapse of his systemic amyloidosis, he has not had recurrence of his penile ulcers many years later.https://www.acpjournals.org/doi/10.7326/aimcc.2022.0526 |
| spellingShingle | Crystal Lihong Yan Fireneh N. Beshah Karen Eliahu James E. Hoffman Systemic Immunoglobulin Light Chain Amyloidosis Presenting as Painful Penile Ulcers Annals of Internal Medicine: Clinical Cases |
| title | Systemic Immunoglobulin Light Chain Amyloidosis Presenting as Painful Penile Ulcers |
| title_full | Systemic Immunoglobulin Light Chain Amyloidosis Presenting as Painful Penile Ulcers |
| title_fullStr | Systemic Immunoglobulin Light Chain Amyloidosis Presenting as Painful Penile Ulcers |
| title_full_unstemmed | Systemic Immunoglobulin Light Chain Amyloidosis Presenting as Painful Penile Ulcers |
| title_short | Systemic Immunoglobulin Light Chain Amyloidosis Presenting as Painful Penile Ulcers |
| title_sort | systemic immunoglobulin light chain amyloidosis presenting as painful penile ulcers |
| url | https://www.acpjournals.org/doi/10.7326/aimcc.2022.0526 |
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