High-dose intravenous vitamin C reduce C-reactive protein levels, fluid retention, and APACHE II scores in patients with moderately severe acute pancreatitis: a prospective, randomized, double-blinded, placebo-controlled study

High-dose intravenous vitamin C reduce C-reactive protein levels, fluid retention, and APACHE II scores in patients with moderately severe acute pancreatitis: a prospective, randomized, double-blinded, placebo-controlled study

Abstract Background The aim of this study was to investigate whether high-dose intravenous vitamin C (HDIVC) could decrease the mortality rate within 28 days among patients moderately severe acute pancreatitis (MSAP) and severe acute pancreatitis (SAP). Methods In this randomized, placebo-controlled...

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Bibliographic Details
Main Authors: Bing Zhao, Wenwu Sun, Yihui Wang, Li Ma, Menglu Gui, Jiaoyan Li, Xianxian Yu, Xing Qi, Ning Ning, Silei Sun, Mengjiao Li, Yi Yao, Tongtian Ni, Juan He, Zhitao Yang, Ying Chen, Huiqiu Sheng, Meihua Shen, Jian Li, Jun Huang, Enqiang Mao
Format: Article
Language:English
Published: SpringerOpen 2025-03-01
Series:Annals of Intensive Care
Subjects:
Severe acute pancreatitis
Vitamin C
Randomized controlled trial
Mortality
C-reactive protein
Fluid retention
Online Access:https://doi.org/10.1186/s13613-025-01437-z
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