Hypoglycemia in type 2 diabetes mellitus patients — cerebral, cognitive, psychosocial and clinical aspects
The review article describes modern approaches to hypoglycemia in diabetes mellitus (DM) patients, its clinical and laboratory diagnostics, and its current classification. Hypoglycemia has the highest impact on cardiovascular morbidity and mortality, including stroke. Cerebral damage in neuroglycope...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Endocrinology Research Centre
2022-07-01
|
| Series: | Сахарный диабет |
| Subjects: | |
| Online Access: | https://www.dia-endojournals.ru/jour/article/view/12840 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849729872307421184 |
|---|---|
| author | K. V. Antonova O. V. Lagoda M. M. Tanashyan |
| author_facet | K. V. Antonova O. V. Lagoda M. M. Tanashyan |
| author_sort | K. V. Antonova |
| collection | DOAJ |
| description | The review article describes modern approaches to hypoglycemia in diabetes mellitus (DM) patients, its clinical and laboratory diagnostics, and its current classification. Hypoglycemia has the highest impact on cardiovascular morbidity and mortality, including stroke. Cerebral damage in neuroglycopenia, as well as neurological aspects in this group of patients, are discussed. The authors describe glycopenia’s influence on cerebral metabolism, counter-regulatory response, and impaired hypoglycemia recognition, as well as modern neuroimaging techniques that may enhance differential diagnostics in complex cases. The epidemiology of neurocognitive disorders in DM patients and their association with hypoglycemic conditions is outlined, together with psychosocial aspects of its consequences — both for the patient and relatives and for the medical professionals. The search for ways to reduce the burden of hypoglycemia from the standpoint of an effective and safe strategy for treating patients with type 2 diabetes does not lose its relevance, and therefore data on the prevalence of hypoglycemic conditions of varying severity when using certain classes of hypoglycemic drugs are presented. A therapeutic approach that maximizes metabolic control while reducing hypoglycemia to a minimum may determine further possibilities for personalized DM management. |
| format | Article |
| id | doaj-art-6aaef4fdcc524284b6e4ed41609b01d2 |
| institution | DOAJ |
| issn | 2072-0351 2072-0378 |
| language | English |
| publishDate | 2022-07-01 |
| publisher | Endocrinology Research Centre |
| record_format | Article |
| series | Сахарный диабет |
| spelling | doaj-art-6aaef4fdcc524284b6e4ed41609b01d22025-08-20T03:09:03ZengEndocrinology Research CentreСахарный диабет2072-03512072-03782022-07-0125328829810.14341/DM1284010958Hypoglycemia in type 2 diabetes mellitus patients — cerebral, cognitive, psychosocial and clinical aspectsK. V. Antonova0O. V. Lagoda1M. M. Tanashyan2Research center of neurologyResearch center of neurologyResearch center of neurologyThe review article describes modern approaches to hypoglycemia in diabetes mellitus (DM) patients, its clinical and laboratory diagnostics, and its current classification. Hypoglycemia has the highest impact on cardiovascular morbidity and mortality, including stroke. Cerebral damage in neuroglycopenia, as well as neurological aspects in this group of patients, are discussed. The authors describe glycopenia’s influence on cerebral metabolism, counter-regulatory response, and impaired hypoglycemia recognition, as well as modern neuroimaging techniques that may enhance differential diagnostics in complex cases. The epidemiology of neurocognitive disorders in DM patients and their association with hypoglycemic conditions is outlined, together with psychosocial aspects of its consequences — both for the patient and relatives and for the medical professionals. The search for ways to reduce the burden of hypoglycemia from the standpoint of an effective and safe strategy for treating patients with type 2 diabetes does not lose its relevance, and therefore data on the prevalence of hypoglycemic conditions of varying severity when using certain classes of hypoglycemic drugs are presented. A therapeutic approach that maximizes metabolic control while reducing hypoglycemia to a minimum may determine further possibilities for personalized DM management.https://www.dia-endojournals.ru/jour/article/view/12840type 2 diabetes mellitushypoglycemiabraincognitive dysfunctionstroke |
| spellingShingle | K. V. Antonova O. V. Lagoda M. M. Tanashyan Hypoglycemia in type 2 diabetes mellitus patients — cerebral, cognitive, psychosocial and clinical aspects Сахарный диабет type 2 diabetes mellitus hypoglycemia brain cognitive dysfunction stroke |
| title | Hypoglycemia in type 2 diabetes mellitus patients — cerebral, cognitive, psychosocial and clinical aspects |
| title_full | Hypoglycemia in type 2 diabetes mellitus patients — cerebral, cognitive, psychosocial and clinical aspects |
| title_fullStr | Hypoglycemia in type 2 diabetes mellitus patients — cerebral, cognitive, psychosocial and clinical aspects |
| title_full_unstemmed | Hypoglycemia in type 2 diabetes mellitus patients — cerebral, cognitive, psychosocial and clinical aspects |
| title_short | Hypoglycemia in type 2 diabetes mellitus patients — cerebral, cognitive, psychosocial and clinical aspects |
| title_sort | hypoglycemia in type 2 diabetes mellitus patients cerebral cognitive psychosocial and clinical aspects |
| topic | type 2 diabetes mellitus hypoglycemia brain cognitive dysfunction stroke |
| url | https://www.dia-endojournals.ru/jour/article/view/12840 |
| work_keys_str_mv | AT kvantonova hypoglycemiaintype2diabetesmellituspatientscerebralcognitivepsychosocialandclinicalaspects AT ovlagoda hypoglycemiaintype2diabetesmellituspatientscerebralcognitivepsychosocialandclinicalaspects AT mmtanashyan hypoglycemiaintype2diabetesmellituspatientscerebralcognitivepsychosocialandclinicalaspects |