Application of physiologically‐based pharmacokinetic modeling to inform dosing decisions for geriatric patients

Application of physiologically‐based pharmacokinetic modeling to inform dosing decisions for geriatric patients

Saved in:

Bibliographic Details
Main Authors:	Lixuan Qian, Ziteng Wang, Mary F. Paine, Eric Chun Yong Chan, Zhu Zhou
Format:	Article
Language:	English
Published:	Wiley 2024-12-01
Series:	CPT: Pharmacometrics & Systems Pharmacology
Online Access:	https://doi.org/10.1002/psp4.13241
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Physiologically Based Pharmacokinetic Modeling of Antibiotics in Children: Perspectives on Model-Informed Precision Dosing
by: Ryota Tanaka, et al.
Published: (2025-05-01)

Prediction of Pharmacokinetics for CYP3A4-Metabolized Drugs in Pediatrics and Geriatrics Using Dynamic Age-Dependent Physiologically Based Pharmacokinetic Models
by: Jing Han, et al.
Published: (2025-02-01)

Toward Precision Dosing of Lamotrigine During Pregnancy: Physiologically Based Pharmacokinetic Modeling and Simulation
by: Yudie Qian, et al.
Published: (2025-05-01)

Pharmacokinetic Model‐Informed Precision Dosing of Natalizumab in Multiple Sclerosis
by: Stefan P. H. van denBerg, et al.
Published: (2025-06-01)

Middle‐Out Physiologically Based Pharmacokinetic Modeling to Support Pediatric Dosing Recommendation for Alectinib
by: Tamara vanDonge, et al.
Published: (2025-06-01)

Effect of SLC22A1 polymorphism on the pharmacokinetics of proguanil in Korean: A semi‐physiologic population pharmacokinetic approach
by: Juyoung Khwarg, et al.
Published: (2024-12-01)

Assessing the Application of Physiologically Based Pharmacokinetic Models in Acute Chemical Incidents
by: Sydney Boone, et al.
Published: (2025-03-01)

Prophylaxis of Gout Flares in Patients with Renal Impairment: Dosing Adjustments with Colchicine Oral Solution Informed by a Pharmacokinetic Model
by: Jaymin Shah, et al.
Published: (2025-06-01)

Reconstructing Organophosphorus Pesticide Doses Using the Reversed Dosimetry Approach in a Simple Physiologically-Based Pharmacokinetic Model
by: Chensheng Lu, et al.
Published: (2012-01-01)

Review of acamprosate pharmacokinetics and dosing strategies
by: Lauren Steil, PharmD, et al.
Published: (2025-04-01)

Development of a physiologically‐based pharmacokinetic model to simulate the pharmacokinetics of intramuscular antiretroviral drugs
by: Sara Bettonte, et al.
Published: (2024-05-01)

Population pharmacokinetics and dosing optimization of imipenem in Chinese elderly patients
by: Jing Wang, et al.
Published: (2025-01-01)

Physiologically Based Pharmacokinetic Modeling to Predict Lamotrigine Exposure in Special Populations to Facilitate Therapeutic Drug Monitoring and Guide Dosing Regimens
by: Ji-Cheng Li, et al.
Published: (2025-04-01)

A physiologically-based pharmacokinetic model for the antibiotic ertapenem
by: Michele L. Joyner, et al.
Published: (2015-09-01)

Corrigendum: Population pharmacokinetics and dosing optimization of imipenem in Chinese elderly patients
by: Jing Wang, et al.
Published: (2025-02-01)

A Population Pharmacokinetic Model to Inform Extension of the Eteplirsen Dosing Regimen Across the Broad DMD Population
by: Yogesh Patel, et al.
Published: (2025-05-01)

Population Pharmacokinetics and Model-Informed Precision Dosing of Clobazam Based on the Developmental and Genetic Characteristics of Children with Epilepsy
by: Yali Tuo, et al.
Published: (2025-06-01)

WCN24-2243 GERIATRIC SYNDROMES AND DECISION MAKING IN PATIENTS REFERRED TO A GERIATRIC NEPHROLOGY CLINIC
by: Jorge I. Fonseca-Correa, et al.
Published: (2024-04-01)

Prediction of SPT-07A Pharmacokinetics in Rats, Dogs, and Humans Using a Physiologically-Based Pharmacokinetic Model and In Vitro Data
by: Xiaoqiang Zhu, et al.
Published: (2024-12-01)

Utility of physiologically based pharmacokinetic modeling to predict inter-antibody variability in monoclonal antibody pharmacokinetics in mice
by: Shufang Liu, et al.
Published: (2023-12-01)

Predicting Pharmacokinetics of Active Constituents in <i>Spatholobi caulis</i> by Using Physiologically Based Pharmacokinetic Models
by: Xiaoyan Liu, et al.
Published: (2024-12-01)

WCN24-555 PHARMACOKINETICS OF SINGLE DOSES OF IPTACOPAN
by: Robert Schmouder, et al.
Published: (2024-04-01)

Application of a Physiologically Based Pharmacokinetic Model to Study Theophylline Metabolism and Its Interactions With Ciprofloxacin and Caffeine
by: A Navid, et al.
Published: (2016-02-01)

Development and Application of Physiologically-Based Pharmacokinetic Model to Predict Systemic and Organ Exposure of Colorectal Cancer Drugs
by: Sara Peribañez-Dominguez, et al.
Published: (2025-01-01)

Pharmacokinetics of difloxacin in Sichuan Shelducks after single or multiple dosing
by: Yang-Guang Jin, et al.
Published: (2025-10-01)

Population pharmacokinetics and dose optimization of ceftazidime in critically ill children
by: Mengting Li, et al.
Published: (2024-11-01)

Population pharmacokinetics modelling for clinical dose adjustment of carboplatin in dogs
by: Jérémy Béguin, et al.
Published: (2024-12-01)

Physiologically Based Pharmacokinetic (PBPK) Modeling of Metabolic Pathways of Bromochloromethane in Rats
by: W. S. Cuello, et al.
Published: (2012-01-01)

Physiological Benefits, Applications, and Future Directions of β-Hydroxy-β-Methylbutyrate (HMB) in Food and Health Industries
by: Sijing Zhou, et al.
Published: (2025-04-01)

Applications of Machine Learning Algorithms in Geriatrics
by: Adrian Stancu, et al.
Published: (2025-08-01)

GastroPlus® as simulating/ conducting software for modeling physiologically-based pharmacokinetics &amp; physiologically based biopharmaceutics.
by: Yasir Qasim Almajidi, et al.
Published: (2025-07-01)

Population pharmacokinetics and dose optimization of voriconazole in patients with COVID-19-associated pulmonary aspergillosis
by: Hui Wang, et al.
Published: (2025-04-01)

Predicting drug–drug interactions and optimal dosing of betrixaban with physiologically based pharmacokinetic modeling in patients with renal impairment who were coadministered with P-glycoprotein inhibitors
by: Xiaoping Yan, et al.
Published: (2025-06-01)

Modeling of pharmacokinetic/pharmacodynamic parameters in regular intermittent intravenous infusion and translational application of the models in personalized antibiotics dosing
by: Xiangqing Song
Published: (2025-07-01)

Vancomycin dosing in neonates: enhancing outcomes using population pharmacokinetics and simulation
by: Sílvia M. Illamola, et al.
Published: (2025-05-01)

Population pharmacokinetics of high-dose methotrexate in patients with primary central nervous system lymphoma
by: Shifeng Wei, et al.
Published: (2025-05-01)

Development of a Physiologically Based Pharmacokinetic Model for Nitrofurantoin in Rabbits, Rats, and Humans
by: Raju Prasad Sharma, et al.
Published: (2023-08-01)

Prediction of pharmacokinetic/pharmacodynamic properties of aldosterone synthase inhibitors at drug discovery stage using an artificial intelligence-physiologically based pharmacokinetic model
by: Mengjun Zhang, et al.
Published: (2025-04-01)

Applications of machine learning in decision analysis for dose management for dofetilide.
by: Andrew E Levy, et al.
Published: (2019-01-01)

Postpartum changes in maternal physiology and milk composition: a comprehensive database for developing lactation physiologically-based pharmacokinetic models
by: Neel Deferm, et al.
Published: (2025-02-01)