Polydatin ameliorates hyperhidrosis by targeting Aqp5 in a mouse model

Polydatin ameliorates hyperhidrosis by targeting Aqp5 in a mouse model

BackgroundPrimary focal hyperhidrosis (PFH) is a neurological dermatological disorder characterized by localized, excessive sweating. Current treatments have limitations, and postoperative compensatory hyperhidrosis remains a concern. Aquaporin 5 (AQP5) and neurologic factors such as Brain-Derived N...

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Bibliographic Details
Main Authors: Jian-Feng Chen, Zhi Feng, Feng-Qiang Yu, Rui-Qin Qiu, Xu Li, Jian-Bo Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Pharmacology
Subjects:
primary focal hyperhidrosis
polydatin
aquaporin 5
sweat glands
treatment
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1589143/full
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