Factors influencing HPV vaccine hesitancy among university students in China: A cross-sectional survey utilizing the 3Cs model

The HPV vaccine, which has been demonstrated to be an effective method of reducing the risk of developing cervical cancer, is still being underutilized among college students in China. To assess the current status of HPV vaccine hesitancy among college students in Guangdong Province after the COVID-...

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Main Authors: Yuancheng He, Xiuqing Zhang, Jie Li, Yuehua Chen, Lin Zhang, Yuehong Wei
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Human Vaccines & Immunotherapeutics
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Online Access:https://www.tandfonline.com/doi/10.1080/21645515.2024.2400750
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author Yuancheng He
Xiuqing Zhang
Jie Li
Yuehua Chen
Lin Zhang
Yuehong Wei
author_facet Yuancheng He
Xiuqing Zhang
Jie Li
Yuehua Chen
Lin Zhang
Yuehong Wei
author_sort Yuancheng He
collection DOAJ
description The HPV vaccine, which has been demonstrated to be an effective method of reducing the risk of developing cervical cancer, is still being underutilized among college students in China. To assess the current status of HPV vaccine hesitancy among college students in Guangdong Province after the COVID-19 outbreak, and to systematically analyze the influencing factors of HPV vaccine hesitancy and construct a prediction model based on the WHO 3Cs model. A cross-sectional web-based survey was conducted in June 2023 among female college students in four cities in Guangdong Province. The data were analyzed using binary logistic regression with a focus on the 3Cs model: Complacency, Convenience, and Confidence. LASSO regression was employed to analyze the variables deemed to be of significance and to construct predictive models. Out of 1399 participants, 86.5% expressed no hesitancy toward HPV vaccination. However, 11.9% exhibited hesitancy, and 1.6% refused vaccination altogether. Factors such as trust in vaccine efficacy, perception of HPV infection risk, price considerations, and constraints like distance or time were significant contributors to hesitancy. Knowledge of the HPV vaccine, socio-demographic characteristics, and the educational level of participants’ mothers also played a role in vaccine hesitancy. It is recommended that targeted interventions be implemented within educational institutions with the aim of raising awareness of cervical cancer and HPV vaccines, simplifying the scheduling of vaccination appointments, and increasing affordability through the implementation of strategic purchasing measures or subsidy schemes.
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spelling doaj-art-6a9d3f45cf5e487bbd5294f29bb81a882025-08-20T03:21:46ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2024-12-0120110.1080/21645515.2024.2400750Factors influencing HPV vaccine hesitancy among university students in China: A cross-sectional survey utilizing the 3Cs modelYuancheng He0Xiuqing Zhang1Jie Li2Yuehua Chen3Lin Zhang4Yuehong Wei5School of Public Health, Sun Yat-sen University, Guangzhou, ChinaBiomedicine and Health, Chinese Academy of Sciences, Guangzhou, ChinaInstitute of Public Health, Guangzhou Medical University & Guangzhou Center for Disease Control and Prevention, Guangzhou, ChinaInstitute of Public Health, Guangzhou Medical University & Guangzhou Center for Disease Control and Prevention, Guangzhou, ChinaDepartment of Parasite and Endemic Disease Prevention and Control, Guangzhou Center for Disease Control and Prevention, Guangzhou, ChinaInstitute of Public Health, Guangzhou Medical University & Guangzhou Center for Disease Control and Prevention, Guangzhou, ChinaThe HPV vaccine, which has been demonstrated to be an effective method of reducing the risk of developing cervical cancer, is still being underutilized among college students in China. To assess the current status of HPV vaccine hesitancy among college students in Guangdong Province after the COVID-19 outbreak, and to systematically analyze the influencing factors of HPV vaccine hesitancy and construct a prediction model based on the WHO 3Cs model. A cross-sectional web-based survey was conducted in June 2023 among female college students in four cities in Guangdong Province. The data were analyzed using binary logistic regression with a focus on the 3Cs model: Complacency, Convenience, and Confidence. LASSO regression was employed to analyze the variables deemed to be of significance and to construct predictive models. Out of 1399 participants, 86.5% expressed no hesitancy toward HPV vaccination. However, 11.9% exhibited hesitancy, and 1.6% refused vaccination altogether. Factors such as trust in vaccine efficacy, perception of HPV infection risk, price considerations, and constraints like distance or time were significant contributors to hesitancy. Knowledge of the HPV vaccine, socio-demographic characteristics, and the educational level of participants’ mothers also played a role in vaccine hesitancy. It is recommended that targeted interventions be implemented within educational institutions with the aim of raising awareness of cervical cancer and HPV vaccines, simplifying the scheduling of vaccination appointments, and increasing affordability through the implementation of strategic purchasing measures or subsidy schemes.https://www.tandfonline.com/doi/10.1080/21645515.2024.2400750HPV vaccinehesitancyinfluencing factors3Cs modeluniversity students
spellingShingle Yuancheng He
Xiuqing Zhang
Jie Li
Yuehua Chen
Lin Zhang
Yuehong Wei
Factors influencing HPV vaccine hesitancy among university students in China: A cross-sectional survey utilizing the 3Cs model
Human Vaccines & Immunotherapeutics
HPV vaccine
hesitancy
influencing factors
3Cs model
university students
title Factors influencing HPV vaccine hesitancy among university students in China: A cross-sectional survey utilizing the 3Cs model
title_full Factors influencing HPV vaccine hesitancy among university students in China: A cross-sectional survey utilizing the 3Cs model
title_fullStr Factors influencing HPV vaccine hesitancy among university students in China: A cross-sectional survey utilizing the 3Cs model
title_full_unstemmed Factors influencing HPV vaccine hesitancy among university students in China: A cross-sectional survey utilizing the 3Cs model
title_short Factors influencing HPV vaccine hesitancy among university students in China: A cross-sectional survey utilizing the 3Cs model
title_sort factors influencing hpv vaccine hesitancy among university students in china a cross sectional survey utilizing the 3cs model
topic HPV vaccine
hesitancy
influencing factors
3Cs model
university students
url https://www.tandfonline.com/doi/10.1080/21645515.2024.2400750
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