MTMR6 downregulation contributes to cisplatin resistance in oral squamous cell carcinoma

MTMR6 downregulation contributes to cisplatin resistance in oral squamous cell carcinoma

Abstract Background The therapeutic effectiveness of cisplatin, a widely used chemotherapy drug for oral squamous cell carcinoma (OSCC), is often compromised by resistance, making it difficult to predict treatment outcomes. The role of myotubularin and myotubularin-related (MTMR) genes in cisplatin...

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Bibliographic Details
Main Authors: Kah Young Lee, Su Young Oh, Heon-Jin Lee, Tae-Geon Kwon, Jin-Wook Kim, Chang-Geol Shin, Su-Hyung Hong, So-Young Choi
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Cancer Cell International
Subjects:
Oral squamous cell carcinoma
Cisplatin resistance
OSCC organoid
Clinical tissues
MTMR6
Hsa-miR-544a
Online Access:https://doi.org/10.1186/s12935-025-03654-9
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