Predicting dupilumab effectiveness with Type-2 biomarkers: A real-world study of severe asthma

Predicting dupilumab effectiveness with Type-2 biomarkers: A real-world study of severe asthma

Background: The therapeutic effectiveness of dupilumab for severe asthma in real-world settings is yet to be prospectively investigated across multiple institutions, and uncertainties persist regarding predictive factors for its effectiveness. We aimed to assess the effectiveness of dupilumab and id...

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Main Authors: Kenji Mizumura, Yasuhiro Gon, Norihiro Harada, Shiho Yamada, Asami Fukuda, Ryosuke Ozoe, Shuichiro Maruoka, Sumiko Abe, Kazuhisa Takahashi, Akihiko Tanaka, Hironori Sagara, Taisuke Akamatsu, Toshihiro Shirai, Katsunori Masaki, Koichi Fukunaga, Konomi Kobayashi, Hiroyuki Nagase, Nobuaki Miyahara, Arihiko Kanehiro, Noboru Kitamura, Naruhiko Sugihara, Fumio Kumasawa, Junko Terada-Hirashima, Masayuki Hojo, Kazuyuki Chibana, Etsuko Tagaya
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Allergology International
Subjects:
Asthma
Dupilumab
Eosinophil
Fractional exhaled nitric oxide
Sputum
Online Access:http://www.sciencedirect.com/science/article/pii/S132389302400087X
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