Longitudinal assessment of tricuspid regurgitation following conduction system pacing
Abstract Tricuspid regurgitation (TR) is a well-known complication of pacemaker implantation (PMI). Recently, the conduction system pacing (CSP) technique, which could avoid the development of ventricular dyssynchrony, was established. However, the impact of CSP on TR is unclear. This study aimed to...
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Nature Portfolio
2025-04-01
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| author | Mitsunori Oida Katsuhito Fujiu Eriko Hasumi Tsukasa Oshima Kunihiro Kani Kohsaku Goto Masaki Hashimoto Toshiya Kojima Yu Shimizu Kenichiro Yamagata Gaku Oguri Issei Komuro |
| author_facet | Mitsunori Oida Katsuhito Fujiu Eriko Hasumi Tsukasa Oshima Kunihiro Kani Kohsaku Goto Masaki Hashimoto Toshiya Kojima Yu Shimizu Kenichiro Yamagata Gaku Oguri Issei Komuro |
| author_sort | Mitsunori Oida |
| collection | DOAJ |
| description | Abstract Tricuspid regurgitation (TR) is a well-known complication of pacemaker implantation (PMI). Recently, the conduction system pacing (CSP) technique, which could avoid the development of ventricular dyssynchrony, was established. However, the impact of CSP on TR is unclear. This study aimed to describe the association between CSP and worsening TR. The data of 110 patients who were given a transthoracic echocardiogram (TTE) before and after PMI were retrospectively analyzed. The severity of TR was classified into four groups. Worsening TR was defined as one or more grade increases in TR. Twenty (18.2%) patients had worsening TR, and 7 patients (6.4%) had TR ≥ moderate after PMI. After comparing the patients with and without CSP, 5 (27.8%) and 15 (16.3%) patients, respectively, had worsening TR, but the frequency did not indicate a significant difference (P = 0.25). The frequency of TR ≥ moderate after PMI in the former group was significantly higher than in the latter group at 3 (16.7%) and 4 (4.3%), respectively (P = 0.05). This study revealed that patients with CSP had a higher frequency of TR ≥ moderate after PMI compared to patients without CSP in the medium term. |
| format | Article |
| id | doaj-art-6a8d1cedb1444ca3bc64a29d2245c5ab |
| institution | OA Journals |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Nature Portfolio |
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| spelling | doaj-art-6a8d1cedb1444ca3bc64a29d2245c5ab2025-08-20T02:17:09ZengNature PortfolioScientific Reports2045-23222025-04-011511710.1038/s41598-025-94614-wLongitudinal assessment of tricuspid regurgitation following conduction system pacingMitsunori Oida0Katsuhito Fujiu1Eriko Hasumi2Tsukasa Oshima3Kunihiro Kani4Kohsaku Goto5Masaki Hashimoto6Toshiya Kojima7Yu Shimizu8Kenichiro Yamagata9Gaku Oguri10Issei Komuro11Department of Cardiovascular Medicine, Graduate School of Medicine, The University of TokyoDepartment of Cardiovascular Medicine, Graduate School of Medicine, The University of TokyoDepartment of Cardiovascular Medicine, Graduate School of Medicine, The University of TokyoDepartment of Cardiovascular Medicine, Graduate School of Medicine, The University of TokyoDepartment of Cardiovascular Medicine, Graduate School of Medicine, The University of TokyoDepartment of Cardiovascular Medicine, Graduate School of Medicine, The University of TokyoDepartment of Cardiovascular Medicine, Graduate School of Medicine, The University of TokyoDepartment of Cardiovascular Medicine, Graduate School of Medicine, The University of TokyoDepartment of Cardiovascular Medicine, Graduate School of Medicine, The University of TokyoDepartment of Cardiovascular Medicine, Graduate School of Medicine, The University of TokyoDepartment of Cardiovascular Medicine, Graduate School of Medicine, The University of TokyoDepartment of Cardiovascular Medicine, Graduate School of Medicine, The University of TokyoAbstract Tricuspid regurgitation (TR) is a well-known complication of pacemaker implantation (PMI). Recently, the conduction system pacing (CSP) technique, which could avoid the development of ventricular dyssynchrony, was established. However, the impact of CSP on TR is unclear. This study aimed to describe the association between CSP and worsening TR. The data of 110 patients who were given a transthoracic echocardiogram (TTE) before and after PMI were retrospectively analyzed. The severity of TR was classified into four groups. Worsening TR was defined as one or more grade increases in TR. Twenty (18.2%) patients had worsening TR, and 7 patients (6.4%) had TR ≥ moderate after PMI. After comparing the patients with and without CSP, 5 (27.8%) and 15 (16.3%) patients, respectively, had worsening TR, but the frequency did not indicate a significant difference (P = 0.25). The frequency of TR ≥ moderate after PMI in the former group was significantly higher than in the latter group at 3 (16.7%) and 4 (4.3%), respectively (P = 0.05). This study revealed that patients with CSP had a higher frequency of TR ≥ moderate after PMI compared to patients without CSP in the medium term.https://doi.org/10.1038/s41598-025-94614-wTricuspid regurgitationCardiac physiologic pacingConduction system pacingPacemaker |
| spellingShingle | Mitsunori Oida Katsuhito Fujiu Eriko Hasumi Tsukasa Oshima Kunihiro Kani Kohsaku Goto Masaki Hashimoto Toshiya Kojima Yu Shimizu Kenichiro Yamagata Gaku Oguri Issei Komuro Longitudinal assessment of tricuspid regurgitation following conduction system pacing Scientific Reports Tricuspid regurgitation Cardiac physiologic pacing Conduction system pacing Pacemaker |
| title | Longitudinal assessment of tricuspid regurgitation following conduction system pacing |
| title_full | Longitudinal assessment of tricuspid regurgitation following conduction system pacing |
| title_fullStr | Longitudinal assessment of tricuspid regurgitation following conduction system pacing |
| title_full_unstemmed | Longitudinal assessment of tricuspid regurgitation following conduction system pacing |
| title_short | Longitudinal assessment of tricuspid regurgitation following conduction system pacing |
| title_sort | longitudinal assessment of tricuspid regurgitation following conduction system pacing |
| topic | Tricuspid regurgitation Cardiac physiologic pacing Conduction system pacing Pacemaker |
| url | https://doi.org/10.1038/s41598-025-94614-w |
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