Mitochondrial Mayhem: How cigarette smoke induces placental dysfunction through MMS19 degradation

Mitochondrial Mayhem: How cigarette smoke induces placental dysfunction through MMS19 degradation

Cigarette smoke (CS) has detrimental effects on placental growth and embryo development, but the underlying mechanisms remain unclear. This study aims to investigate the impact of CS on trophoblast cell proliferation and regulated cell death (RCD) by examining its interference with iron-sulfur clust...

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Bibliographic Details
Main Authors: Pei Zhou, Feng Jin, Shenshen Yao, Ben Sun, Ni Sun, Hongbo Guan, Xiaomei Liu
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Cigarette smoke
Placenta
ICSs
MMS19
SMAD pathway
Mitochondrial damage
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651325000648
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