Exploring the use of the RISK21 approach for Indigenous community-based human health risk assessments: two case studies

Indigenous peoples in North America are disproportionately exposed to environmental contaminants and may face elevated health risks related to unique socio-cultural ties to the land. Conventional human health risk assessment (HHRA) methods do not account for these unique contexts. Regulators (i.e.,...

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Main Authors: Katherine Chong, Madisan Chavez, Ave Dersch, John Doyle, Margaret Eggers, JoRee LaFrance, Myra J Lefthand, Findlay MacDermid, Claire McAuley, Vanessa Simonds, Sara L Young, Niladri Basu
Format: Article
Language:English
Published: Canadian Science Publishing 2025-01-01
Series:FACETS
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Online Access:https://facetsjournal.com/doi/10.1139/facets-2024-0085
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author Katherine Chong
Madisan Chavez
Ave Dersch
John Doyle
Margaret Eggers
JoRee LaFrance
Myra J Lefthand
Findlay MacDermid
Claire McAuley
Vanessa Simonds
Sara L Young
Niladri Basu
author_facet Katherine Chong
Madisan Chavez
Ave Dersch
John Doyle
Margaret Eggers
JoRee LaFrance
Myra J Lefthand
Findlay MacDermid
Claire McAuley
Vanessa Simonds
Sara L Young
Niladri Basu
author_sort Katherine Chong
collection DOAJ
description Indigenous peoples in North America are disproportionately exposed to environmental contaminants and may face elevated health risks related to unique socio-cultural ties to the land. Conventional human health risk assessment (HHRA) methods do not account for these unique contexts. Regulators (i.e., Health Canada, US EPA) have called for the development of more ethical and efficient HHRA approaches, but to our knowledge no such approaches have been designed in consideration of Indigenous community contexts. RISK21 is a new HHRA approach gaining regulatory attention. We present two case studies piloting RISK21’s use in collaboration with three unique communities (Cold Lake First Nations, Chipewyan Prairie First Nation, Apsáalooke/Crow Nation). Our objectives are first, reflect upon the benefits and challenges of using RISK21 in these contexts; second, compare RISK21-based to conventional assessments; and third, ideate adaptations and improvements to the approach. The RISK21-based analyses had similar descriptive results to the original conventional assessments, including when using less information. We found RISK21 useful for rapid chemical assessment and visually representing data from multiple sources. We recommend areas where RISK21 (and other next-generation HHRA approaches) might be improved for Indigenous community contexts, including increasing the community relevance of communication tools and incorporating holistic and non-conventional information.
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spelling doaj-art-6a581b3099f548fab7a474f2d1ffd0752025-08-20T01:58:00ZengCanadian Science PublishingFACETS2371-16712025-01-011011610.1139/facets-2024-0085Exploring the use of the RISK21 approach for Indigenous community-based human health risk assessments: two case studiesKatherine Chong0Madisan Chavez1Ave Dersch2John Doyle3Margaret Eggers4JoRee LaFrance5Myra J Lefthand6Findlay MacDermid7Claire McAuley8Vanessa Simonds9Sara L Young10Niladri Basu11Centre for Indigenous Peoples’ Nutrition and Environment, McGill University, Ste-Anne-de-Bellevue, QC, CanadaCrow Environmental Health Steering Committee, Crow Reservation, MT, USAMoccasin Flower Consulting, Slave Lake, AB, CanadaCrow Environmental Health Steering Committee, Crow Reservation, MT, USACrow Environmental Health Steering Committee, Crow Reservation, MT, USACrow Environmental Health Steering Committee, Crow Reservation, MT, USACrow Environmental Health Steering Committee, Crow Reservation, MT, USACold Lake First Nations, Lands and Resources Department, AB, CanadaIntrinsik Corp., Calgary, AB, CanadaCrow Environmental Health Steering Committee, Crow Reservation, MT, USACrow Environmental Health Steering Committee, Crow Reservation, MT, USACentre for Indigenous Peoples’ Nutrition and Environment, McGill University, Ste-Anne-de-Bellevue, QC, CanadaIndigenous peoples in North America are disproportionately exposed to environmental contaminants and may face elevated health risks related to unique socio-cultural ties to the land. Conventional human health risk assessment (HHRA) methods do not account for these unique contexts. Regulators (i.e., Health Canada, US EPA) have called for the development of more ethical and efficient HHRA approaches, but to our knowledge no such approaches have been designed in consideration of Indigenous community contexts. RISK21 is a new HHRA approach gaining regulatory attention. We present two case studies piloting RISK21’s use in collaboration with three unique communities (Cold Lake First Nations, Chipewyan Prairie First Nation, Apsáalooke/Crow Nation). Our objectives are first, reflect upon the benefits and challenges of using RISK21 in these contexts; second, compare RISK21-based to conventional assessments; and third, ideate adaptations and improvements to the approach. The RISK21-based analyses had similar descriptive results to the original conventional assessments, including when using less information. We found RISK21 useful for rapid chemical assessment and visually representing data from multiple sources. We recommend areas where RISK21 (and other next-generation HHRA approaches) might be improved for Indigenous community contexts, including increasing the community relevance of communication tools and incorporating holistic and non-conventional information.https://facetsjournal.com/doi/10.1139/facets-2024-0085human health risk assessmentnew approach methodologies (NAMs)Indigenous communitiesRISK21cumulative risk assessmenttraditional food
spellingShingle Katherine Chong
Madisan Chavez
Ave Dersch
John Doyle
Margaret Eggers
JoRee LaFrance
Myra J Lefthand
Findlay MacDermid
Claire McAuley
Vanessa Simonds
Sara L Young
Niladri Basu
Exploring the use of the RISK21 approach for Indigenous community-based human health risk assessments: two case studies
FACETS
human health risk assessment
new approach methodologies (NAMs)
Indigenous communities
RISK21
cumulative risk assessment
traditional food
title Exploring the use of the RISK21 approach for Indigenous community-based human health risk assessments: two case studies
title_full Exploring the use of the RISK21 approach for Indigenous community-based human health risk assessments: two case studies
title_fullStr Exploring the use of the RISK21 approach for Indigenous community-based human health risk assessments: two case studies
title_full_unstemmed Exploring the use of the RISK21 approach for Indigenous community-based human health risk assessments: two case studies
title_short Exploring the use of the RISK21 approach for Indigenous community-based human health risk assessments: two case studies
title_sort exploring the use of the risk21 approach for indigenous community based human health risk assessments two case studies
topic human health risk assessment
new approach methodologies (NAMs)
Indigenous communities
RISK21
cumulative risk assessment
traditional food
url https://facetsjournal.com/doi/10.1139/facets-2024-0085
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