A cisplatin prodrug-based self-assembling ozone delivery nanosystem sensitizes radiotherapy in triple-negative breast cancer

A cisplatin prodrug-based self-assembling ozone delivery nanosystem sensitizes radiotherapy in triple-negative breast cancer

Lacking therapeutic targets highlights the crucial roles of chemotherapy and radiotherapy in the clinical management of triple-negative breast cancer (TNBC). To relieve the side effects of the chemoradiotherapy combination regimen, we design and develop a self-assembled micelle nanosystem consisting...

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Bibliographic Details
Main Authors: Tianyue Xu, Dan Zheng, Meixu Chen, Linlin Song, Zhihui Liu, Yan Cheng, Yujie Zhao, Liwen Huang, Yixuan Li, Zhankun Yang, Cong Li, Biao Dong, Jing Jing, Hubing Shi
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Cisplatin
Prodrug
Radiotherapy
Controlled-release system
Ozone
Triple-negative breast cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383525001558
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