Asymptomatic Esophageal Eosinophilia in an 11-Year-Old with Severe Persistent Asthma

Asymptomatic esophageal eosinophilia (aEE) is a rare presentation, where patients have increased eosinophils in esophageal mucosa but lack any esophagus-related symptoms. Cases of aEE have only been documented in adults, and little is known about its clinical significance and whether treatment is wa...

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Main Authors: Casey E. Hofstaedter, Runa Watkins, Nidhi Kotwal
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Case Reports in Pediatrics
Online Access:http://dx.doi.org/10.1155/2023/6678918
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author Casey E. Hofstaedter
Runa Watkins
Nidhi Kotwal
author_facet Casey E. Hofstaedter
Runa Watkins
Nidhi Kotwal
author_sort Casey E. Hofstaedter
collection DOAJ
description Asymptomatic esophageal eosinophilia (aEE) is a rare presentation, where patients have increased eosinophils in esophageal mucosa but lack any esophagus-related symptoms. Cases of aEE have only been documented in adults, and little is known about its clinical significance and whether treatment is warranted. We report a case of an 11-year-old patient with uncontrolled severe persistent asthma who underwent flexible bronchoscopy and upper endoscopy as a part of complete aerodigestive evaluation. Elevated intraepithelial eosinophils in the esophageal mucosa were noted, suggesting an aEE-like presentation. This case documents a pediatric patient with aEE and highlights the importance of combined aerodigestive assessment with pulmonology and gastroenterology teams for the evaluation of severe asthma.
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spelling doaj-art-6a40bcf278ac447bbd98cbe9be03540b2025-08-20T02:06:04ZengWileyCase Reports in Pediatrics2090-68112023-01-01202310.1155/2023/6678918Asymptomatic Esophageal Eosinophilia in an 11-Year-Old with Severe Persistent AsthmaCasey E. Hofstaedter0Runa Watkins1Nidhi Kotwal2Medical Scientist Training ProgramDivision of Gastroenterology and HepatologyDivision of Pulmonology and AllergyAsymptomatic esophageal eosinophilia (aEE) is a rare presentation, where patients have increased eosinophils in esophageal mucosa but lack any esophagus-related symptoms. Cases of aEE have only been documented in adults, and little is known about its clinical significance and whether treatment is warranted. We report a case of an 11-year-old patient with uncontrolled severe persistent asthma who underwent flexible bronchoscopy and upper endoscopy as a part of complete aerodigestive evaluation. Elevated intraepithelial eosinophils in the esophageal mucosa were noted, suggesting an aEE-like presentation. This case documents a pediatric patient with aEE and highlights the importance of combined aerodigestive assessment with pulmonology and gastroenterology teams for the evaluation of severe asthma.http://dx.doi.org/10.1155/2023/6678918
spellingShingle Casey E. Hofstaedter
Runa Watkins
Nidhi Kotwal
Asymptomatic Esophageal Eosinophilia in an 11-Year-Old with Severe Persistent Asthma
Case Reports in Pediatrics
title Asymptomatic Esophageal Eosinophilia in an 11-Year-Old with Severe Persistent Asthma
title_full Asymptomatic Esophageal Eosinophilia in an 11-Year-Old with Severe Persistent Asthma
title_fullStr Asymptomatic Esophageal Eosinophilia in an 11-Year-Old with Severe Persistent Asthma
title_full_unstemmed Asymptomatic Esophageal Eosinophilia in an 11-Year-Old with Severe Persistent Asthma
title_short Asymptomatic Esophageal Eosinophilia in an 11-Year-Old with Severe Persistent Asthma
title_sort asymptomatic esophageal eosinophilia in an 11 year old with severe persistent asthma
url http://dx.doi.org/10.1155/2023/6678918
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AT runawatkins asymptomaticesophagealeosinophiliainan11yearoldwithseverepersistentasthma
AT nidhikotwal asymptomaticesophagealeosinophiliainan11yearoldwithseverepersistentasthma