20-Hydroxyecdysone Modulates Bmp53-Mediated Apoptosis Regulation by Suppressing Mdm2-like-Dependent Ubiquitination in Silkworm, <i>Bombyx mori</i>

20-Hydroxyecdysone Modulates Bmp53-Mediated Apoptosis Regulation by Suppressing Mdm2-like-Dependent Ubiquitination in Silkworm, <i>Bombyx mori</i>

In the silkworm, 20-hydroxyecdysone (20E) induces apoptosis and autophagy, driving larval organ degeneration and remodeling. This mechanism may be a potential target for eco-friendly strategy for insect pests. However, a major challenge in harnessing this approach lies in the insufficient understand...

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Bibliographic Details
Main Authors: Meixian Wang, Dingding Han, Luyang Xiang, Jiahao Wang, Benteng Luo, Xingjia Shen
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Insects
Subjects:
apoptosis
Bmp53
Mdm2-like
ubiquitination
20E
Online Access:https://www.mdpi.com/2075-4450/16/5/544
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